Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2146/ajhp040580 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparative HPTLC fingerprinting profile and GC-MS analysis of raw and purified () by purification method.
J Complement Integr Med
May 2021
Department of Dravyaguna Vijnanam, Government Ayurveda College, Thiruvananthapuram, Kerala, India.
Background: is an oleo gum resin obtained from the plant (Arn.) Bhand., used in medicines for various ailments like anti-inflammatory conditions, hyperlipidemia, thyroid disorders etc.
View Article and Find Full Text PDFGuggulu and Triphala for the Treatment of Hypercholesterolaemia: A Placebo-Controlled, Double-Blind, Randomised Trial.
Complement Med Res
September 2021
Department of Internal Medicine, University of Brescia and Spedali Civili di Brescia, Brescia, Italy.
Background: Several herbs are used for lowering high blood cholesterol levels in traditional medicines including Indian Medicine (Ayurveda). We aimed to assess the short-term effects of the combination of Guggulu (Commiphora mukul) and Triphala (Terminalia chebula, Terminalia belerica, and Phyllanthus emblica) on serum cholesterol in healthy subjects with hypercholesterolaemia.
Patients And Methods: This was a parallel randomised double-blind controlled trial that included 90 individuals at low-moderate cardiovascular risk.
Efficacy and tolerability of a nutraceutical combination of red yeast rice, guggulipid, and chromium picolinate evaluated in a randomized, placebo-controlled, double-blind study.
Complement Ther Med
January 2020
PT. Novell Pharmaceutical Laboratories, Jl. Raya Pos Pengumben No. 8, West Jakarta, 11550, Jakarta, Indonesia.
Hypercholesterolemia is the major risk factor in the development of coronary heart disease. Coronary heart disease is a leading cause of morbidity and mortality in many countries worldwide. An increasing attention is now paid to nutraceuticals development for prevention and cure of dyslipidemia, especially for patients who do not wish to use chemical statins.
View Article and Find Full Text PDFSafety and Efficacy of NC120 for Improving Lipid Profile: A Double Blind Randomized Controlled Trial.
Acta Med Indones
January 2019
Dept. of Pharmacology, Faculty of Medicine Universitas Indonesia -Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Background: the use of statin to lower blood cholesterol is often associated with bothersome adverse effects such as myopathy and liver dysfunction. NC120 is herbal lipid lowering drug containing red yeast rice (RYR) extract, guggulipid, and chromium picolinate, and expected to have better safety profile. The aim of this study was to evaluate the efficacy and safety profiles of NC120 in lowering blood lipid.
View Article and Find Full Text PDFGugulipid causes hypercholesterolemia leading to endothelial dysfunction, increased atherosclerosis, and premature death by ischemic heart disease in male mice.
PLoS One
October 2017
Department of Nutrition, Diabetes and Metabolism, Pontificia Universidad Católica de Chile, Santiago, Chile.
For proper cholesterol metabolism, normal expression and function of scavenger receptor class B type I (SR-BI), a high-density lipoprotein (HDL) receptor, is required. Among the factors that regulate overall cholesterol homeostasis and HDL metabolism, the nuclear farnesoid X receptor plays an important role. Guggulsterone, a bioactive compound present in the natural product gugulipid, is an antagonist of this receptor.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!