The research was aimed to study the effects of a 30 minute exposure to 2.5 ATA with 100% O2-inhalation on lactate concentration after muscular fatigue from incremental exercise on a cycle ergometer The subjects were 60 male naval cadets aged 20-23 years whose physical fitness was equivalent to the average athletes. All volunteers participated in the first VO2 max exercise test to obtain their baseline data and randomly assigned into 3 groups of 20. The 3 groups were: Rest recovery group (RR), Oxygen recovery group (OR), and the Hyperbaric oxygenation (HBO2) recovery group (HR). The volunteers took the incremental exercise test (Ordinary Lamp Protocol) on a cycle ergometer to exhaustion, then rested according to the above assigned groups. Blood samples were taken from each volunteer before the experiment, at exhaustion and every 5-minute intervals after the exhaustion for 30 minutes and immediately assayed for lactate concentration. The results showed significant decrease of blood lactate concentration at 15, 20 and 25 minutes intervals after the exhaustion in the HR group compared to the others. It might be initially concluded that HBO2 enhanced the rate of lactate removal from peripheral blood vessels, therefore it shortened the recovery time.
Download full-text PDF |
Source |
---|
Cytotechnology
April 2025
Cellular and Molecular Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Because acute kidney injuries (AKI) are one of the critical health problems worldwide, studies on the risk factors, mechanisms, and treatment strategies seem necessary. Glycerol (GLY), known to induce cell necrosis via myoglobin accumulation in renal tubules, is widely used as an AKI model. This study aimed to evaluate the protective effects of gallic acid (GA) against GLY-induced AKI.
View Article and Find Full Text PDFFront Cell Infect Microbiol
January 2025
Emergency Medicine Clinical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Background: Community-acquired pneumonia (CAP) poses a significant health threat to the elderly population, leading to high morbidity and mortality rates. Serum ferritin, a critical indicator of iron metabolism, plays a pivotal role in inflammation and immune regulation. Nevertheless, its specific prognostic relevance in elderly patients with CAP remains unclear.
View Article and Find Full Text PDFInt J Nanomedicine
January 2025
Advanced Diagnostics and Therapeutics Institute, Health Sector, King Abdulaziz City for Science and Technology (KACST), Riyadh, 11442, Saudi Arabia.
Introduction: Wound treatment is a significant health burden in any healthcare system, which requires proper management to minimize pain and prevent bacterial infections that can complicate the wound healing process.
Rationale: There is a need to develop innovative therapies to accelerate wound healing cost-effectively. Herein, two polymer-based nanofibrous systems were developed using poly-lactic-co-glycolic-acid (PLGA) and polyvinylpyrrolidone (PVP) loaded with a combination of an antibiotic (Fusidic acid, FA) and a local anesthetic (Lidocaine, LDC) via electrospinning technique for an expedited healing process by preventing bacterial infections while reducing the pain sensation.
AME Case Rep
October 2024
Department of Oncology, Wenzhou Traditional Chinese Medicine Hospital of Zhejiang Chinese Medical University, Wenzhou, China.
Background: Hyperammonemic encephalopathy caused by high-dose infusion of 5-fluorouracil (5-FU) is a rare adverse reaction in rectal cancer patients with an incidence rate of 5.7%. Although the patient could be restored to normal after supportive treatments, the occurrence of this side effect was still inevitable.
View Article and Find Full Text PDFACS Sens
January 2025
School of Basic Medical Science, Xi'an Key Laboratory of Pathogenic Microorganism and Tumor Immunity, Xi'an Medical University, Xi'an 710021, China.
To enhance exploration on tumor stem-like cells (TSCs) without altering their cellular biological characteristics, researchers advocate for application of single-cell-derived tumor-spheres (STSs). TSCs are regulated by their surrounding microenvironment, making it crucial to simulate a tumor microenvironment to facilitate STS formation. Recently, exosomes that originated from the tumor microenvironment have emerged as a promising approach for mimicking the tumor microenvironment.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!