Dissemination of CTX-M-type extended-spectrum beta-lactamase genes to unusual hosts.

J Clin Microbiol

Dipartimento di Biologia Molecolare, Laboratorio di Fisiologia e Biotecnologia dei Microrganismi, Università di Siena, Policlinico Santa Maria alle Scotte, 53100 Siena, Italy.

Published: August 2005

A Citrobacter amalonaticus and a Morganella morganii producing the CTX-M-1 extended-spectrum beta-lactamase (ESBL) were isolated from an area where this enzyme is now widespread in Escherichia coli. This is the first report of CTX-M-1 in the former species. In both cases the ESBL determinant was possibly acquired by these unusual hosts in vivo, after coinfection with E. coli strains carrying conjugative plasmids encoding CTX-M-1.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1233897PMC
http://dx.doi.org/10.1128/JCM.43.8.4183-4185.2005DOI Listing

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