Stroke-complicated endocarditis with positive lupus anticoagulant--a case report.

Twenty to 40% of patients with infective endocarditis (IE) suffer from neurologic complications. Also many and various markers of immunologic activation have been reported in patients with IE and no history of autoimmune or other rheumatologic diseases. The authors present a case of a patient suffering from IE complicated with major cerebrovascular event with concomitant appearance of lupus anticoagulant (LAC). After successful antibiotic treatment there was major clinical improvement with disappearance of LAC. LAC could be added to the list of immunologic markers appearing in the course of infective endocarditis.