[Infectious endocarditis: a current overview on an "old" disease].

Rev Port Cir Cardiotorac Vasc

Serviço de Infecciologia, Hospital de Santa Maria, Lisboa.

Published: January 2006

The infectious endocarditis, first described by William Osler in 1885, is and still remains nowadays as a severe disease, with difficult diagnosis and coursing with high morbi-mortality rates. However, along the years, the disease showed significant modifications in its epidemiology, risk factors, etiologic agents, new study and diagnostic tests and new treatment modalities, medical and surgical, which are the subject of an extensive review by the author, based on an accumulated clinical experience during the last three decades.

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  • The study examined the relationship between serum bicarbonate levels and 28-day mortality in critically ill patients with infective endocarditis using data from the MIMIC-IV database.
  • Patients with higher serum bicarbonate levels upon ICU admission showed significantly lower mortality rates, suggesting that bicarbonate levels can be a potential prognostic marker.
  • The findings indicate that monitoring bicarbonate levels could help assess risk and guide the clinical management of patients with infective endocarditis.
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