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What do ultrasound vocalizations really mean in rats with different origins of pain?
Pain Rep
February 2025
Institute for Biomedical Sciences of Pain, Tangdu Hospital, The Fourth Military Medical University, Xi'an, P. R. China.
Objectives: This study is to assess how 22 kHz and 50 kHz spontaneous ultrasound vocalization (USV) calls would be affected by different origins of pain so as to validate the use of USV in pain studies.
Methods: Five well-established rat models of pain were used to evaluate various parameters of spontaneous 22 kHz and 50 kHz calls in adult male rats in terms of both acute and chronic or inflammatory and neuropathic or somatic and visceral origins. The effects of local lidocaine blockade of the injection site and intraperitoneal administration of antidepressant (amitriptyline) and anticonvulsant (gabapentin) were examined as well in typical inflammatory and neuropathic pain models, respectively.
Risk of swallowing disorders in patients with chronic rhinosinusitis and nasal polyposis in comparison to healthy controls: a Survey of 50 cases.
Eur Arch Otorhinolaryngol
December 2024
Department of Otolaryngology-Head and Neck Surgery, Rhinology and Endoscopic Skull Base Surgery, American University of Beirut Medical Center, 11-0236, Riad El Solh, Beirut, 1107 2020, Lebanon.
Purpose: To investigate the risk of swallowing disorders and the frequency and intensity of vocal tract symptoms in patients with chronic rhinosinusitis and nasal polyposis (CRSwNP).
Methods: Adult patients diagnosed with CRSwNP presenting to the rhinology clinic of a tertiary referral center between March 2023 and March 2024, were recruited. Patients with acute or recent history of respiratory tract infections, tonsillitis, pharyngitis or otitis, were excluded.
Identifying Paediatric Populations with Increased Risk for Oropharyngeal Dysphagia in Acute and Critical Care Settings: A Scoping Review.
Dysphagia
December 2024
School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.
Dysphagia is common in hospitalised children. Clarity regarding its prevalence is required to direct service needs. This review reports oropharyngeal dysphagia prevalence in children admitted to acute and/or critical care, following acute illness, medical or surgical intervention.
View Article and Find Full Text PDFAcute Bilateral Vocal Cord Paralysis in a Patient With Anti-Leucine-Rich Glioma-Inactivated 1 (LGI1) Limbic Encephalitis.
Cureus
December 2024
Neurology, UT Health San Antonio, San Antonio, USA.
Autoimmune encephalitis is a disorder characterized by an autoantibody-mediated process that leads to brain inflammation. It is associated with neurological symptoms including cognitive issues, psychiatric problems, seizures, and autonomic dysfunctions. Anti-leucine-rich glioma-inactivated 1 limbic encephalitis (anti-LGI1 LE) is a rare type of autoimmune LE with a unique presentation, comprising neuropsychiatric disturbances, sleep disorders, and faciobrachial dystonic seizures (FBDS).
View Article and Find Full Text PDFVocal cord dysfunction: Does laryngeal adduction on laryngoscopy predict disease severity and response to laryngeal retraining therapy?
Laryngoscope Investig Otolaryngol
December 2024
Department of Otolaryngology, College of Medicine University of Arizona Tucson Arizona USA.
Introduction: Vocal cord dysfunction (VCD) is a complex disorder characterized by episodic adduction of the vocal folds during inspiration and expiration, which can lead to dyspnea, wheezing, cough, and acute-onset respiratory distress. Currently, there is a lack of standardized criteria among treating physicians across multiple disciplines, including otolaryngologists, pulmonologists, allergists, and speech and language pathologists, for diagnosis and treatment of VCD, although laryngeal-respiratory retraining therapy (LRT) has emerged as the preferred treatment modality.
Objective: In the present study, we examined the efficacy of LRT in patients presenting with a clinical diagnosis of VCD in the presence and absence of laryngeal adduction on laryngoscopy.
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