Objective: To optimize the molding formula of refined Xiong-gui sustained release pills, types and assorted dosages of water-soluble and non water-soluble drug carrier were studied.
Method: An orthogonal design was performed to sift the pill formulation. The processing conditions were determining in terms of roundness, hardness, viscosity, fluidity, easily drop.
Result And Conclusion: According to the final optimal formula, the amount of drug release can be detected instantly, while remaining over 80% at 10 h.
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[Study on preparation of refined Xiong-gui sustained release pills].
Zhongguo Zhong Yao Za Zhi
May 2005
Institute of Chinese Material Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China.
Objective: To optimize the molding formula of refined Xiong-gui sustained release pills, types and assorted dosages of water-soluble and non water-soluble drug carrier were studied.
Method: An orthogonal design was performed to sift the pill formulation. The processing conditions were determining in terms of roundness, hardness, viscosity, fluidity, easily drop.
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