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Aetiology of Vascular Purpura in a Single Centre Experience: Contribution of Clinical and Paraclinical Data.
Mediterr J Rheumatol
March 2024
CHU Mongi Slim, La Marsa, Tunisia.
Background: Vascular purpura can be the clinical expression of infectious, inflammatory, drug-related, neoplastic, and endocrine pathologies. To date, there is no consensus codifying the investigation of vascular purpura, especially when it is isolated.
Patients And Methods: We proposed to study through a retrospective study of 73 cases of vascular purpura, occurring during the period 2004-2019 in our internal medicine department, the contribution of various clinical and paraclinical data to the aetiological diagnosis of vascular purpura.
[Adult IgA vasculitis].
Rev Prat
December 2023
Service de médecine interne, CHU de Tours, Tours, France.
ADULT IGA VASCULITIS. IgA vasculitis previously named rheumatoid purpura is a rare systemic vasculitis in adults involving small vessels and associated with the presence of immunoglobulin A deposits. IgA vasculitis is often triggerd by infections, taking medication and vaccination.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to analyze bleeding and clotting complications in patients with systemic AL-amyloidosis, focusing on their relation to lab results reflecting hemostasis.
- In a group of 40 newly diagnosed patients, significant findings included that 50% showed skin and mucosal bleeding, while 17.5% had thrombotic events before therapy started, with a noted link between these two complications.
- The research highlighted that most patients with bleeding had concurrent hypercoagulation, particularly in cases with kidney damage, and overall, hypercoagulation was more prevalent compared to hypocoagulation among the patients.
Rare manifestations of cryoglobulinemic vasculitis: a case report.
Front Immunol
October 2023
Department of Nephrology, Dialysis, and Transplantation, University of Picardie Jules Verne, Amiens University Hospital, Amiens, France.
Introduction: Cryoglobulinemic vasculitis is a type of small vessel vasculitis diseases that can cause dysfunction in multiple organs. It is characterized by general symptoms, often accompanied by nonspecific cutaneous, articular, neurological, and renal manifestations. Diagnosing cryoglobulinemia through biological testing can be time-consuming and sometimes yields negative results, making diagnosis challenging.
View Article and Find Full Text PDF[Cryoglobulinemic vasculitis].
Rev Prat
December 2022
Département de médecine interne et immunologie clinique, groupe hospitalier La Pitié-Salpêtrière, AP-HP, Paris, France. Sorbonne Université. INSERM UMRS 959, I3 Immunologie-immunopathologie-immunothérapie, Sorbonne Université, Paris.
Cryoglobulins are immunoglobulins that precipitate in vitro when serum is incubated at temperatures lower than 37°C. Cryoglobulins are classified under three subgroups according to their components. Cryoglobulinemic vasculitis corresponds to manifestations associated with vascular occlusion by cryoglobulins or inflammatory manifestations induced by the deposition of cryoglobulins containing immune complex.
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