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Influence of the combination of mineral water and ciprofloxacin on the interaction form of individual representatives of the upper respiratory tract mucosa microbiota .
Ann Agric Environ Med
December 2024
Strategies and Programmess, State Institute Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of the Ministry of Health, Odessa, Ukraine.
Introduction And Objective: Elimination irrigation therapy has been proposed as a potential treatment for upper respiratory tract infections, particularly after the COVID-19 pandemic, due to its antiviral properties and mechanical cleansing effects. Additionally, a combination of mineral water with antibiotic therapy has shownto be effective in improving the course clinical infection and positively impact the immune system, potentially enhancing the normal state of microbiota state. The aim of the study is to investigate the influence of elimination-irrigation therapy using a combination of mineral water and ciprofloxacin on the interaction form of individual microbiota species of the upper respiratory tract mucous membrane.
View Article and Find Full Text PDFGlobal burden of antimicrobial resistance in lower respiratory infections in 2021: a systematic analysis.
Int J Antimicrob Agents
December 2024
School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China. Electronic address:
Objectives: The research aimed to provide a worldwide evaluation of antimicrobial resistance (AMR), focusing specifically on AMR related to lower respiratory infections (LRI).
Methods: The data were derived from the Global Antimicrobial Resistance Burden 2021 (GARB 2021). Two counterfactuals were utilized to estimate the deaths attributable to AMR and the deaths associated with AMR.
Exploring frameworks for quantitative risk assessment of antimicrobial resistance along the food chain.
EFSA J
December 2024
Istituto Zooprofilattico Sperimentale del Lazio e della Toscana (IZSLT) Rome Italy.
is one of the most reported causes of bacterial gastroenteritis worldwide. Birds are the predominant reservoirs for thermotolerant , therefore consumption of contaminated and undercooked poultry products represents one of the major transmission routes for campylobacteriosis. In addition to foodborne diseases, another relevant public challenge is the silent pandemic of antimicrobial resistance (AMR), impacting also the food chain.
View Article and Find Full Text PDFSignificance of Targeted Antimicrobial Prophylaxis Using Rectal-culture Selective Screening Media Prior to Transrectal Prostate Biopsy: A Multicenter, Randomized Controlled Trial.
Urology
December 2024
Department of Urology, Shimane University Faculty of Medicine, Shimane, Japan; The Japanese Research Group for Urinary Tract Infection (JRGU), Nishinomiya, Japan.
Objective: To examine whether antimicrobial prophylaxis based on screening rectal cultures using selective media prevented acute bacterial prostatitis following transrectal prostate biopsy (TRPB).
Methods: In this multicenter, randomized controlled trial, we enrolled 403 patients undergoing TRPB with low risks of infectious complications. Patients were randomized into a cultured group (CG) or no cultured group (NCG).
Antimicrobial stewardship in the Federal Bureau of Prisons: Combining prospective audit and feedback with formulary changes to reduce inappropriate fluoroquinolone use.
Am J Health Syst Pharm
December 2024
College of Pharmacy, Roseman University of Health Sciences, Henderson, NV, and Reserve Commissioned Corps, United States Public Health Service, Washington, DC, USA.
Article Synopsis
- * Antimicrobial stewardship programs have shown benefits mainly in hospitals, but there's less evidence for their effectiveness in other settings, such as prisons.
- * A study at the Federal Bureau of Prisons revealed that implementing targeted audits and formulary restrictions led to a significant 46.4% reduction in fluoroquinolone prescriptions, demonstrating that these strategies can effectively improve antibiotic use outside traditional healthcare environments.
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