There have been various studies on the prevention of falls and fractures in the elderly, from which we should select and implement effective prevention measures. The present report reviewed systematic review, meta-analysis and randomized controlled trial studies to give evidence-based recommendations for the fracture prevention.
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Association between cardiovascular health and osteoporotic fractures: a national population-based study.
Sci Rep
January 2025
Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, NO. 172 Tong Zi Po Road, Yuelu District, Changsha, 410006, Hunan, China.
Osteoporotic fractures are a major public health concern, particularly among the aging population, as they significantly contribute to morbidity, mortality, and reduced quality of life. While cardiovascular health (CVH) has traditionally been linked to cardiovascular disease outcomes, emerging evidence suggests it may also influence bone health. This study investigates the association between CVH, as measured by the Life's Essential 8 (LE8) score, and the prevalence of osteoporotic fractures in U.
View Article and Find Full Text PDFEZH2 serves as a viable therapeutic target for myeloma-induced osteolytic bone destruction.
Nat Commun
January 2025
Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.
Myelomatous bone disease is a complication characterized by lytic bone lesions, reduced bone formation, bone pain, and increased fracture risk. Understanding these underlying mechanisms is crucial for developing effective therapeutic approaches. Here we show the role of enhancer of zeste homolog 2 (EZH2) in bone lesions induced by myeloma cells.
View Article and Find Full Text PDF[Pathology and Acute Phase Treatment of Osteoporotic Vertebral Fractures:Indications and Techniques for Vertebroplasty].
No Shinkei Geka
January 2025
Department of Neurosurgery, Takeda General Hospital.
Vertebroplasty has shown excellent analgesic effects in patients with osteoporotic vertebral fractures. In Japan, percutaneous vertebroplasty, balloon kyphoplasty, and vertebral body stenting are commonly performed. All of these techniques require precise transpedicular vertebral puncture and complete cement filling without leakage.
View Article and Find Full Text PDFFood Insecurity Is Common in the Orthopaedic Trauma Population.
J Am Acad Orthop Surg
January 2025
From the Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, IA (Willey, Miller, Temperly, Martin, Leary, Marsh, and Glass), Slocum Research and Education Foundation, Eugene, OR (Owen, Fitzpatrick, and Kirkpatrick), the Department of Health Policy and Management, Johns Hopkins Bloomberg school of Public Health, Baltimore, MD (Reider), and the Department of Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, TN (Trochez, Wrenn, and Ponce).
Introduction: Food insecurity is the condition of limited access to healthy and safe food. Malnutrition resulting from food insecurity is a concern particularly in the surgical population due to the association with impaired healing. This aim of this study was to report the incidence and risk factors for food insecurity in the orthopaedic trauma population.
View Article and Find Full Text PDFAnalysis of pediatric hand injuries in a tertiary care children's hospital.
J Pediatr Orthop B
March 2025
Biostatistics, Ankara University Faculty of Medicine, Ankara, Turkey.
Pediatric hand traumas are common injuries in childhood. The incidence and type of injury vary with age. In our country, there are only two publications in which only crush is examined in etiology.
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