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Transcatheter Pulmonary Flow Restrictors: Current Trends and Future Perspectives.
Catheter Cardiovasc Interv
January 2025
Pediatrics & Medicine, Weill Cornell Medicine Chief International Patients Services & Chair, Sidra Department Cardiovascular Diseases, University of Jordan, Amman, Jordan.
Article Synopsis
- Transcatheter Pulmonary Flow Restrictors (TPFRs) are innovative devices for managing pulmonary blood flow in congenital heart disease, yet there is a lack of detailed studies examining their variety and crucial design features.
- * The review consolidates current knowledge on TPFRs, highlights significant design considerations, identifies gaps in medical practice, and suggests future research avenues to improve these devices.
- * An analysis of 82 TPFR implants revealed challenges like complications with microvascular plugs, including issues with sizing, device migration, and thrombosis, while emphasizing the need for devices that can be safely removed and reduce risks like embolization and inflammation.
PTFE Stent Membrane Based on the Electrospinning Technique and Its Potential for Replacing ePTFE.
ACS Appl Bio Mater
December 2024
National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, No. 199 Ren'ai Road, Industrial Park, Suzhou 215123, PR China.
Expanded poly(tetrafluoroethylene) (ePTFE), obtained by the paste extrusion-stretching method, is a commonly used stent membrane material for the treatment of arterial stenosis or aneurysm in clinical practice. However, the structure of ePTFE is nonfibrous, which is not friendly to cells, and the equipment consumes a lot of energy and often requires the use of flammable and toxic lubricants. In this study, electrospinning was used to prepare PTFE vascular stent membranes, following plasma treatment, dopamine, and heparin grafting to obtain an anticoagulant surface.
View Article and Find Full Text PDFA novel intravascular bioartificial pancreas device shows safety and islet functionality over 30 days in nondiabetic swine.
Am J Transplant
November 2024
Isla Technologies, Inc, San Carlos, California, USA. Electronic address:
In this study using a discordant, xenogeneic, transplant model we demonstrate the functionality and safety of the first stent-based bioartificial pancreas (BAP) device implanted endovascularly into an artery, harnessing the high oxygen content in blood to support islet viability. The device is a self-expanding nitinol stent that is coated with a bilayer of polytetrafluoroethylene that forms channels to hold islets embedded in a hydrogel. We completed a 1-month study in the nondiabetic swine model (N = 3) to test the safety of the device and to assess islet functionality after device recovery.
View Article and Find Full Text PDFAntegrade Fenestration During Thoracic Endovascular Aortic Repair for Preserving Isolated Left Vertebral Artery.
EJVES Vasc Forum
October 2024
Department of Vascular Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Article Synopsis
- An isolated left vertebral artery (ILVA) is often affected by aortic arch pathologies, and preserving its blood flow during endovascular repair can be challenging, with no clear consensus on the best strategy.
- This case report details a successful endovascular procedure in a 72-year-old man with an ILVA, where a novel technique called antegrade needle-assisted fenestration was used to revascularize the artery without traditional surgical methods.
- The patient had a favorable outcome, with follow-up imaging showing a patent ILVA and good aortic remodeling, suggesting this technique could be a valuable option for similar cases.
Multidisciplinary Approach to Direct Segmental Artery Revascularization to Prevent Spinal Cord Ischemia Associated With Endovascular Thoracoabdominal Aortic Repair.
J Endovasc Ther
November 2024
Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Keck Hospital of USC, University of Southern California, Los Angeles, CA, USA.
Purpose: Despite advances in complex endovascular aortic repair techniques, spinal cord ischemia (SCI) remains a devastating complication following endovascular thoracoabdominal aortic repairs. Novel strategies to preserve key intercostal/lumbar arteries have been described. We report our early results of patients who underwent direct intercostal/lumbar artery revascularization using endovascular incorporation of fenestrations/branches or extra-anatomic approaches for fenestrated-branched endovascular aortic repairs (FBEVARs).
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