AI Article Synopsis
- The study identified the presence of ACTH and similar receptor-like molecules in various tissues of the sea bass, Dicentrarchus labrax, at multiple developmental stages post-hatching (2 to 24 days).
- Both ACTH and its receptor-like molecules were found to share a similar distribution across different tissues, indicating their potential importance in developmental processes.
- LPS treatment at specific stages (8 and 24 days post-hatching) triggered the release and induction of ACTH-like molecules, highlighting their role in regulating body homeostasis during the early life of the fish, especially before lymphoid cell maturation occurs by 30 days post-hatching.
Article Abstract
ACTH and ACTH receptor-like molecules were found at the examined stages of development (2, 4, 8, 12, 18, and 24 days post-hatching) in yolk sac, pronephros tubules, interrenal tissue, thymus, liver, spleen, cardinal veins, and skin of the teleost fish Dicentrarchus labrax. ACTH and the related receptor-like molecules show a similar distribution. LPS treatment at two different stages (8 and 24 days post-hatching) provoked both a release and an induction of ACTH-like molecules, suggesting an important role of this peptide to control the modifications in body homeostasis during the first period of the sea bass' life, i.e., 30 days post-hatching, before the lymphoid cells have reached complete maturation.
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| http://dx.doi.org/10.1016/j.ygcen.2005.02.021 | DOI Listing |
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