Achieving Magnet designation is a journey to excellence. Although excellence is never quite attained, Magnet organizations have nursing leaders who are able to implement innovative nursing programs that attract and retain nursing's best and brightest. These leaders have raised the bar on excellence and are able to demonstrate performance that is in the upper quartile among benchmarks. Even though financial pressures require astute budgetary skill, these leaders do fund research and education programs, are involved in shared leadership/governance activities, and are thus able to demonstrate fiscal accountability in the process. Nurse leaders in Magnet organizations have a highly engaged professional staff as evidenced by active participation in shared governance activities. These leaders have not only created interdisciplinary approaches to patient care and clinical documentation, acuity, and research but also they have hardwired these activities into the fabric of the organization.
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Altered thalamotemporal structural connectivity is associated with autistic traits in children with ASD.
Behav Brain Res
January 2025
Center for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, WA, United States of America.
Background: Thalamocortical functional and structural connectivity alterations may contribute to clinical phenotype of Autism Spectrum Disorder. As previous studies focused mainly on thalamofrontal connections, we comprehensively investigated between-group differences of thalamic functional networks and white matter pathways projecting also to temporal, parietal, occipital lobes and their associations with core and co-occurring conditions of this population.
Methods: A total of 38 children (19 with Autism Spectrum Disorder) underwent magnetic resonance imaging and behavioral assessment.
Long-range directional growth of neurites induced by magnetic forces.
Acta Biomater
January 2025
School of Life Sciences, Keele University, Staffordshire, UK. Electronic address:
The ability to control the growth and orientation of neurites over long distances has significant implications for regenerative therapies and the development of physiologically relevant brain tissue models. In this study, the forces generated on magnetic nanoparticles internalised within intracellular endosomes are used to direct the orientation of neuronal outgrowth in cell cultures. Following differentiation, neurite orientation was observed after 3 days application of magnetic forces to human neuroblastoma (SH-SY5Y) cells, and after 4 days application to rat cortical primary neurons.
View Article and Find Full Text PDFTranscranial resection of falcine meningiomas by complete endoscopy with the assistance of intraoperative ultrasound.
Neurosurg Rev
January 2025
Department of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218, Hefei, 230022, P.R. China.
Transcranial neurosurgery assisted by endoscopy and intraoperative ultrasound (IOUS) has become an effective approach for real-time visualization and guidance during tumor resection. This study explores the application of these techniques in falcine meningioma (FM) resection, assessing their feasibility and safety. Eleven FM patients underwent transcranial endoscopic resection with IOUS assistance.
View Article and Find Full Text PDFFunctional connectivity gradients and neurotransmitter maps among patients with mild cognitive impairment and depression symptoms.
J Psychiatry Neurosci
January 2025
From the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China (X. Liu, Chen, K. Liu, Yan, Wu); the Wenzhou Key Laboratory of Structural and Functional Imaging, Wenzhou, Zhejiang Province, China (X. Liu, Chen, K. Liu, Yan); the Jinhua Municipal Central Hospital, Jinhua, Zhejiang 321000, China (Chen); the Hebei General Hospital, Shijiazhuang, Hebei 050050, China (Cheng); the Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang 310012, China (Wei, Hou, Li, Guo); the Zhoushan Second People's Hospital, Zhoushan, Zhejiang 316000, China (Guo)
Background: Both depressive symptoms and neurotransmitter changes affect the characteristics of functional brain networks in clinical patients. We sought to explore how brain functional grading is organized among patients with mild cognitive impairment and depressive symptoms (D-MCI) and whether changes in brain organization are related to neurotransmitter distribution.
Methods: Using 3 T magnetic resonance imaging (MRI) we acquired functional MRI (fMRI) data from patients with D-MCI, patients with mild cognitive impairment without depression (nD-MCI), and healthy controls.
The impact of clinical seizures and adverse brain MRI patterns in neonates with hypoxic-ischemic encephalopathy and abnormal neurodevelopment.
Clinics (Sao Paulo)
January 2025
Department of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea. Electronic address:
Introduction: This study aimed to investigate the associations among seizures, clinical characteristics, and brain injury on Magnetic Resonance Imaging (MRI) in infants with Hypoxic Ischemic Encephalopathy (HIE), and to determine whether these findings can predict unfavorable neurodevelopmental outcomes.
Method: Clinical and electrographic seizures were assessed by amplitude-integrated electroencephalogram, and the extent of brain injury was evaluated by using MRI. At 12‒24 months of age, developmental impairment or death was assessed.
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