Renalase, a catecholamine-metabolizing hormone from the kidney.

Cell Metab

Medical Faculty of the Charite, Franz Volhard Clinic, HELIOS Klinikum-Berlin, Max Delbruck Center for Molecular Medicine, Berlin, Germany.

Published: June 2005

A novel flavin adenine dinucleotide-dependent amine oxidase that is secreted by the kidney, circulates in the blood, and modulates cardiac function and systemic blood pressure has recently been discovered. Renalase appears to be a hormone that metabolizes catecholamines, and its discovery will facilitate our understanding of sympathetic regulation.

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http://dx.doi.org/10.1016/j.cmet.2005.05.008DOI Listing

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