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Nanosecond Molecular Motion in pHP1α Liquid-Liquid Phase Separation Captured by Solid-State NMR.
J Phys Chem Lett
January 2025
Centre of High Field NMR Spectroscopy and Imaging, Nanyang Technological University, 21 Nanyang Link, Singapore 637371.
The relationship among protein structure, function, and dynamics is fundamental to biological activity, particularly in more complex biomolecular systems. Solid-state and solution-state NMR techniques offer powerful means to probe these dynamics across various time scales. However, standard assumptions about molecular motion are often challenged in phase-separated systems like phosphorylated heterochromatin protein 1 alpha (pHP1α), which exhibit both solid- and solution-like characteristics.
View Article and Find Full Text PDF[Gastroenterology and hepatology : what's new in 2024].
Rev Med Suisse
January 2025
Unité de gastroentérologie, Service de médecine interne, Hôpital Riviera Chablais, 1847 Rennaz.
The year 2024 was rich in developments in the field of hepatology, gastroenterology, and interventional endoscopy. New molecules have been developed for the treatment of metabolic steatohepatitis, primary biliary cirrhosis, and inflammatory bowel diseases. Technological progress now makes it possible to perform screening measurements for portal hypertension directly under echo-endoscopic guidance and to extend the use of intraluminal stents to surgically modified anatomies.
View Article and Find Full Text PDFNatural pigments: innovative extraction technologies and their potential application in health and food industries.
Front Pharmacol
January 2025
Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Natural pigments, or natural colorants, are frequently utilized in the food industry due to their diverse functional and nutritional attributes. Beyond their color properties, these pigments possess several biological activities, including antioxidant, anti-inflammatory, anticancer, antibacterial, and neuroprotective effects, as well as benefits for eye health. This review aims to provide a timely overview of the potential of natural pigments in the pharmaceutical, medical, and food industries.
View Article and Find Full Text PDFThe role of government fiscal and tax incentives in green technology innovation and enterprise development: implications for human health and hygiene.
Front Public Health
January 2025
College of Business Administration, Chongqing Vocational and Technical University of Mechatronics, Chongqing, China.
Purpose: This study aims to examine how government fiscal and tax incentives facilitate the development and application of green technologies, promoting corporate environmental responsibility and improving public health and hygiene.
Methods: The study utilizes empirical data from listed enterprises in the new energy automobile industry between 2018 and 2023. A multiple regression model is used to assess the effects of government subsidies and tax incentives on green technological innovation and enterprise growth, controlling for various factors such as enterprise size and R&D investment.
Integration of data sets for modelling gender violence and perception of insecurity.
Data Brief
February 2025
Technological University Dublin, Faculty of Engineering and Built Environment, School of Surveying and Construction Innovation, Room 334.1, Bolton Street, D01 K822, Dublin, Ireland.
The dataset offers a comprehensive information to analyse cities and neighbourhood that are potentially unsafe for women, this information has been collected for four cities: Toluca (Mexico), Valencia (Spain), Dublin (Ireland) and San Francisco (USA). The collection includes quantitative and qualitative variables obtained and processed from open data, georeferenced publications from a social media platform, and points located through participatory mapping sessions. The data is structured in raw format, organized by country and city, and categorized according to the data source used while processing, which allows unrestricted access with most data analysis software and it does not depend on specific licenses.
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