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United States and European Union laws demand separate clinical studies in children as a condition for drugs' marketing approval. Justified by carefully framed pseudo-scientific wordings, more so the European Medicines Agency than the United States Food and Drug Administration, "Pediatric Drug Development" is probably the largest abuse in medical research in history. Preterm newborns are immature and vulnerable, but they grow.
View Article and Find Full Text PDFPrediction of urinary tract infection using machine learning methods: a study for finding the most-informative variables.
BMC Med Inform Decis Mak
January 2025
Department of Pediatrics, School of Medicine, Ekbatan Hospital, Hamadan University of Medical Sciences, Hamadan, Iran.
Background: Urinary tract infection (UTI) is a frequent health-threatening condition. Early reliable diagnosis of UTI helps to prevent misuse or overuse of antibiotics and hence prevent antibiotic resistance. The gold standard for UTI diagnosis is urine culture which is a time-consuming and also an error prone method.
View Article and Find Full Text PDFMeasuring a family sense of coherence: a rasch-based study extending dyadic data analyses.
BMC Palliat Care
January 2025
RISE Research Institutes of Sweden, Division Safety and Transport, Measurement Science and Technology, Göteborg, Sweden.
Background: Family sense of coherence (FSOC) seems to reduce distress in the family and promote the well-being of the family. Therefore, getting accurate measurements for families with long-term illnesses is of particular interest. This study explores dyadic data analysis from the dyadic- and single-informant perspectives, and the measurement properties of the FSOC-S12 according to the Rasch model.
View Article and Find Full Text PDFApplying principles of adult learning to rural health electives in a medical school curriculum.
BMC Med Educ
January 2025
Department of Rural Health, Melbourne Medical School, The University of Melbourne, 49 Graham Street, Shepparton, VIC, 3630, Australia.
The health disparities between rural and urban populations in Australia, driven by socioeconomic, environmental, and healthcare access factors, highlight the urgent need for rural-focused medical education. The Melbourne Medical School's Rural Health Discovery program addresses this need by integrating adult learning principles within a redesigned curriculum that includes the Rural Health Foundations and Integrating Rural Health topics. These Discovery topics engage medical students from diverse backgrounds through a blend of self-directed learning, problem-solving, and immersive clinical placements in rural settings.
View Article and Find Full Text PDFImplementing a workplace participatory approach to support working caregivers in balancing their work, private life and informal care: results of a process evaluation.
BMC Public Health
January 2025
National Institute for Public Health and the Environment, Center for Prevention, Lifestyle and Health, Department Behaviour and Health, Antonie van Leeuwenhoeklaan 9, Bilthoven, 3721 MA, The Netherlands.
Background: Many organizations are faced with growing numbers of employees who combine their jobs with informal caregiving responsibilities. To support working caregivers in maintaining a good balance between work, private life and informal care, a workplace participatory approach (PA) intervention was implemented in four Dutch organizations. This study's aims were to evaluate the degree of PA implementation, contextual factors influencing implementation, and stakeholder experiences with the PA.
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