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Nano-sized heterogeneous photocatalyst FeO@V/TiO-catalyzed synthesis and antimycobacterial evaluation of 2-substituted benzimidazoles.
Mol Divers
January 2025
School of Life Sciences, Jilin University, 2699 Qianjin Street, Changchun, 130012, People's Republic of China.
The 2-substituted benzimidazole has emerged as a promising heterocyclic compound in the field of drug design. In pursuit of more sustainable photocatalysts for 2-substituted benzimidazole synthesis, the method for coating FeO with V-doped TiO was presented. On the base of characterizing composition, morphology, and properties, the prepared nano-sized FeO@V/TiO composites were used as a heterogeneous photocatalyst to catalyze the synthesis of 2-substituted benzimidazoles under light.
View Article and Find Full Text PDFFibroblast activation protein peptide-targeted NIR-I/II fluorescence imaging for stable and functional detection of hepatocellular carcinoma.
Eur J Nucl Med Mol Imaging
January 2025
Department of Hepatobiliary Surgery and Liver Transplantation Center, The Fifth Affiliated Hospital of Sun Yat-Sen University, 52 Mei Hua East Road, Zhuhai, 519000, China.
Purpose: Cancer-associated fibroblasts (CAFs) are the primary stromal component of the tumor microenvironment in hepatocellular carcinoma (HCC), affecting tumor progression and post-resection recurrence. Fibroblast activation protein (FAP) is a key biomarker of CAFs. However, there is limited evidence on using FAP as a target in near-infrared (NIR) fluorescence imaging for HCC.
View Article and Find Full Text PDFFacile fabrication of biocompatible carbon dots from egg white by one-step neutralization heat reaction: a capillary array-based fluorimetric strategy for high-throughput detection of total iron ions in fish blood.
Analyst
January 2025
Huzhou Key Laboratory of Medical and Environmental Application Technologies, School of Life Sciences, Huzhou University, Huzhou 313000, China.
Water-soluble and biocompatible protein carbon dots (P-CDs) were simply prepared from egg white by a rapid one-step neutralization heat reaction. Unexpectedly, the thus-fabricated P-CDs could present excitation-dependent tunable fluorescence that could be quenched specifically by Fe and Fe ions with obvious color changes. A high-throughput fluorimetric platform was thereby developed by coating the P-CDs onto a capillary array for detection of total iron ions in fish blood samples, with a linear concentration range of 0.
View Article and Find Full Text PDFAnalysis of the economically justifiable price of mepolizumab in adults with asthma in Colombia.
J Asthma
January 2025
Department of Pharmacology and Toxicology, University of Antioquia, Medellín, Colombia.
Introduction: Asthma imposes a critical economic burden on health systems, especially with the incorporation of new drugs. Recently, mepolizumab has been approved to prevent exacerbations in patients with eosinophilic asthma, however their high cost constitutes a barrier for their use, especially in middle- and low-income countries. This study aimed to estimate the economically justifiable price of mepolizumab for preventing exacerbations in patients with severe asthma in Colombia.
View Article and Find Full Text PDFThin film microextraction of PAHs from wastewater samples using an oxine modified iron mesh followed by dispersive liquid-liquid microextraction prior to gas chromatography analysis.
Anal Methods
January 2025
Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran.
In the present research, an attempt has been made to develop a new thin film microextraction method for the extraction of several polycyclic aromatic hydrocarbons from aqueous samples collected from different industrial units prior to their analysis by gas chromatography combined with a flame ionization detector. In this approach, a thin iron mesh was modified by the formation of iron(II) oxinate on its surface and used for the extraction of analytes without an additional sorbent. For this purpose, first, the mesh was immersed in a sulfuric acid solution and then transferred into an 8-hydroxy quinoline (oxine) solution dissolved in ammonia solution.
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