Concentration of dopamine and serotonin metabolites (HVA and 5-HIAA) in the CSF was evaluated before and after pharmacological treatment in 19 patients with different neuropsychiatric diseases. In every case a reciprocal modification of the two metabolites occurred after treatment. The result supports the hypothesis of a functional balance between the monoaminergic systems in the central nervous system.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC490433 | PMC |
| http://dx.doi.org/10.1136/jnnp.42.12.1159 | DOI Listing |
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