Polymorphisms in exon 1 of the MBL-2 gene, resulting in reduced plasma levels of mannose binding lectin, were significantly overrepresented in 23 patients with primary antibody deficiency and culture-proven mycoplasma infections (P = 0.0038). This association persisted with the inclusion of a further nine suspected (doxycycline-responsive) cases (P = 0.0087). The lectin was shown to bind to three strains of mycoplasma.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201221 | PMC |
| http://dx.doi.org/10.1128/IAI.73.8.5238-5240.2005 | DOI Listing |
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