Objectives: A seasonal rhythm of reproduction is evident in humans. Herein it was investigated whether also the cessation of woman's fertile life follows a seasonal rhythm.
Methods: A retrospective study was performed on 2436 women in postmenopause for more than 12 months, in our menopause centres. Time of menopause was stratified for month and season. The variation was compared to the seasonal rhythm of 14,310 conceptions.
Results: The onset of menopause was more frequent (p<0.0001) in winter (32.5%) than in spring (20.8%), autumn (20.3%) and summer (26.2%), in which a minor peak was also observed (p<0.0001 vs. spring and autumn). The two peaks were temporally coincident with the transitions between the high to low and low to high rate of conceptions.
Conclusions: The present data show that in women, like reproduction also the onset of menopause shows a seasonal modulation.
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http://dx.doi.org/10.1016/j.maturitas.2004.10.002 | DOI Listing |
Obesity (Silver Spring)
March 2025
Eli Lilly and Company, Indianapolis, Indiana, USA.
Objective: Increases in adiposity and adverse changes in adipose distribution commonly occur in women during midlife and with the onset of menopause. This post hoc analysis assessed body weight changes with tirzepatide by reproductive stage.
Methods: Women participants from SURMOUNT-1, -3, and -4 randomized to tirzepatide (15 mg or maximum tolerated dose) or placebo were retrospectively categorized as being in the pre-, peri-, or post-menopause stages.
Future Oncol
March 2025
hSarcoma Medical Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College, New York, NY, USA.
Climacteric
March 2025
Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Sleep is a cornerstone of health, playing an integral role in both physiological and psychological functions. However, it is vulnerable to a variety of factors including menopause. According to available research, the onset of the menopause transition may not necessarily worsen sleep architecture and could even enhance it, leading to conflict between assessment of subjective and objective sleep complaints.
View Article and Find Full Text PDFEcol Evol
March 2025
Fisheries and Oceans Canada Pacific Biological Station Nanaimo British Columbia Canada.
Long-term field studies have been invaluable in the study of ecology and evolution; however, for particularly long-lived species, even long-term studies often rely on estimated ages, for example when investigating demographic processes. One approach is to estimate unknown birth dates from the known timing of other life-history events. Building on previous methods, we update estimation techniques for Northern Resident killer whales (NRKW; ) as part of an ongoing long-term study that began in 1973.
View Article and Find Full Text PDFFront Pharmacol
February 2025
Department of Psychiatry, HER Centre Australia, The School of Translational Medicine, Monash University, Melbourne, VIC, Australia.
Female gonadal hormones, particularly estrogen and progesterone, are not only central to reproductive health but also play a crucial role in regulating mood, cognition, and overall brain health. These hormones have a significant impact on the central nervous system, influencing key processes such as neurotransmission, neuroplasticity, and brain development. Increasing evidence shows that hormonal fluctuations contribute to the onset and progression of mental health disorders that disproportionately affect women, particularly premenstrual dysphoric disorder (PMDD), postnatal depression (PND), and menopausal depression.
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