AI Article Synopsis
- The study aimed to determine if SARS-CoV could be excreted through the digestive system of infected individuals.* -
- Through testing various stool and sewage samples, researchers found SARS-CoV RNA in some stool samples from symptomatic SARS patients, but no live virus was detected in any samples.* -
- The findings suggest that while infectious SARS-CoV wasn't found, the presence of its RNA in stool indicates potential for viral transmission via the digestive system.*
Article Abstract
Aim: To study whether severe acute respiratory syndrome coronavirus (SARS-CoV) could be excreted from digestive system.
Methods: Cell culture and semi-nested RT-PCR were used to detect SARS-CoV and its RNA from 21 stool and urine samples, and a kind of electropositive filter media particles was used to concentrate the virus in 10 sewage samples from two hospitals receiving SARS patients in Beijing in China.
Results: It was demonstrated that there was no live SARS-CoV in all samples collected, but the RNA of SARS-CoV could be detected in seven stool samples from SARS patients with any one of the symptoms of fever, malaise, cough, or dyspnea, in 10 sewage samples before disinfection and 3 samples after disinfection from the two hospitals. The RNA could not be detected in urine and stool samples from patients recovered from SARS.
Conclusion: Nucleic acid of SARS-CoV can be excreted through the stool of patients into sewage system, and the possibility of SARS-CoV transmitting through digestive system cannot be excluded.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434667 | PMC |
| http://dx.doi.org/10.3748/wjg.v11.i28.4390 | DOI Listing |
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