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Experiences, perceptions and ethical considerations of the malaria infection study in Thailand.
BMC Med Ethics
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Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Thunphayathai, Bangkok, 10400, Thailand.
Background: Thailand has made significant progress in malaria control efforts in the past decade, with a decline in the number of reported cases. However, due to cross-border movements over the past 5 years, reported malaria cases in Thailand have risen. The Malaria Infection Study in Thailand (MIST) involves deliberate infection of healthy volunteers with Plasmodium vivax malaria parasites, and the assessment of the efficacy of potential vaccine and drug candidates in order to understand acquired protection against malaria parasites.
View Article and Find Full Text PDFElectromagnetism and thermostability of CrCsynthesised with high-temperature and high-pressure quenching method.
J Phys Condens Matter
January 2025
Institute of High Pressure Physics, School of Physical Science and Technology, Ningbo University, Ningbo, 315211, People's Republic of China, Ningbo, Zhejiang, 315211, CHINA.
The interactions between the carbon skeleton and the metal atoms of a binary transition metal carbide (BTMC) are particular interest for industrial applications with openning physics and chemitry questions, especially in magnetoelectric (ME) functional materials and cemented carbides. Chromium and carbon BTMCs are a series of intermetallic compounds with typical chemical formulas and sharepolycrystalline powder c somehromium special characteristics.and carbon as precursors, In this paper,and synthesized s we usedingle-phase bluk Cr7C3 (orthorhombic, with space group: Pnma) with high density and good crystallinity by means of high-temperature and high-pressure quenching method (HTHPQM).
View Article and Find Full Text PDFEfficacy and Safety of Proactive Therapy with 2% Crisaborole Ointment in Children with Mild-to-Moderate Atopic Dermatitis: A Randomized Controlled Study.
Paediatr Drugs
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Department of Dermatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Background: The effectiveness of crisaborole for proactive treatment of atopic dermatitis (AD) is not well established.
Objectives: This study aims to investigate the efficacy and safety of a proactive treatment strategy with 2% crisaborole ointment for managing mild-to-moderate AD in children.
Patients And Methods: In this 16-week randomized-controlled trial, children aged 2-17 years with mild-to-moderate AD were enrolled.
Assessment of Reperfusion Efficacy of Altelyse Versus Actilyse in Patients with Acute Myocardial Infarction: A Phase 3, Randomized, Double-Blinded, Non-inferiority Clinical Trial.
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Department of Cardiology, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Primary percutaneous coronary intervention (PPCI) and fibrinolytic or thrombolytic therapy are common treatments for ST-elevation myocardial infarction (STEMI). Primary percutaneous coronary intervention is more effective than thrombolytic therapy, but fibrinolytic therapy is still a preferable option for patients with limited access to healthcare. Alteplase is a tissue plasminogen activator (tPA) used to treat acute myocardial infarction, acute ischemic stroke, and pulmonary embolism.
View Article and Find Full Text PDFAmplifying Electron-Donor Signal of the "Water Gate" Enabled Low Detection Ability of a Field-Effect Transistor-Based Humidity Sensor.
Anal Chem
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School of Physics and Optoelectronics, Xiangtan University, Xiangtan 411105, PR China.
Low humidity detection down to the parts per million level is urgently demanded in various industrial applications. The hardly detected tiny electrical signal variations caused by a very small amount of water adsorption are one of the intrinsic reasons that restrain the detection limit of the humidity sensors. Herein, a carbon-based field-effect transistor (FET) humidity sensor utilizing adsorbed water as the dual function of a sensing gate and analyte was proposed.
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