The development and application of laser-based tissue microdissection techniques has provided a major impetus to the sensitive and specific molecular analysis of solid tissues and tumors. This chapter provides an overview of the different laser-based microdissection systems and an introduction to the principles involved in the function and applications of these individual systems.
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http://dx.doi.org/10.1385/1-59259-853-6:003 | DOI Listing |
Biomimetics (Basel)
December 2024
Department of Surgery, Division of Ophthalmology, University of Sherbrooke, Sherbrooke, QC J1G 2E8, Canada.
Three-dimensional bioprinting (3DP) is transforming the field of regenerative medicine by enabling the precise fabrication of complex tissues, including the retina, a highly specialized and anatomically complex tissue. This review provides an overview of 3DP's principles, its multi-step process, and various bioprinting techniques, such as extrusion-, droplet-, and laser-based methods. Within the scope of biomimicry and biomimetics, emphasis is placed on how 3DP potentially enables the recreation of the retina's natural cellular environment, structural complexity, and biomechanical properties.
View Article and Find Full Text PDFChem Biodivers
December 2024
Institute of Basic and Applied Sciences, Egypt-Japan University of Science and Technology, New Borg El Arab, Alexandria, Egypt.
Breast cancer ranks as the second most widespread form of cancer globally. Currently, combination therapy is being actively employed in clinical practice to augment the efficiency of anticancer treatment. Hence, the objective of this study was to assess the therapeutic efficacy of a combination of femtosecond laser-based photodynamic therapy (PDT) utilizing two distinct photosensitizers (PSs), zinc phthalocyanine tetrasulfonate (ZnPcS) and α,β,χ,δ porphyrin-Tetrakis (1-methylpyridinium-4-yl) p-Toluenesulfonate porphyrin (TMPyP) in conjunction with doxorubicin chemotherapeutic agent, on mammary carcinomas experimentally induced in female mice using 7,12-dimethylbenz[a] anthracene (DMBA).
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
March 2025
Lancaster Medical School, Lancaster University, LA1 4AT, United Kingdom; Bristol School of Anatomy, Bristol University, BS2 8EJ, United Kingdom. Electronic address:
Background: The NHS spends £4.3 billion annually to address musculoskeletal conditions, encompassing age-related bone disorders like osteoarthritis and osteoporosis. Traditional X-ray diagnostic methods are commonly employed for bone disorder diagnosis, primarily assessing gross anatomical bone structure changes.
View Article and Find Full Text PDFLasers Med Sci
November 2024
Faculty of Medicine and Health, Sydney Dental School, The University of Sydney, Camperdown, NSW, 2006, Australia.
Lasers Surg Med
December 2024
R&D, IPG Medical, Marlborough, Massachusetts, USA.
Objectives: Laser-based endoscopic procedures present special challenges to deliver energy for ablation or coagulation of target tissues. When optical fiber-target quasi-contact (< 0.5 mm distance) cannot be maintained or is undesirable, the creation of intervening vapor bubbles and channels provide for the necessary transmission of laser energy to the target.
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