AI Article Synopsis
- In utero gangrene of an extremity due to arterial thrombosis is uncommon, often linked to infants of diabetic mothers with poorly managed diabetes.
- Changes in blood coagulation factors and low plasminogen activity are thought to contribute to this condition.
- A case is presented of an infant with upper extremity gangrene, confirmed by imaging and leading to amputation; unfortunately, the baby experienced severe complications and died ten days later.
Article Abstract
In utero gangrene of an extremity because of an arterial thrombosis is rare. More than 20% of the reported cases concern infants of diabetic mothers (IDM) with poor control of diabetes. Changes in coagulation related to deviation of clotting factors and low plasminogen activity may be the cause. We report a case of an IDM who presented at birth with upper extremity gangrene. The Dopplersonography has shown missing pulsations and thrombosis of a.brachialis sin, which was confirmed after amputation of the arm on the 5th day. The postoperative period was complicated by septicaemia, necrotising enterocolitis and disseminated intravasal coagulation resulting in the baby's death 10 days after birth.
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