AI Article Synopsis
- The study aimed to examine the structure of lymph vessels in gastric cancer tissues and how it relates to cancer spread (metastasis).
- Researchers analyzed tissues from 32 gastric cancer cases, noting morphological changes in lymph vessels and capillaries.
- Findings indicated that lymph vessels in cancerous areas showed larger sizes and that swollen lymph vessels help cancer cells spread, particularly through well-formed lymph capillaries in nearby tissues.
Article Abstract
Objective: To investigate the morphology of the lymph vessels in human gastric carcinoma tissues and the relationship to cancer metastasis.
Methods: Morphological changes of the lymph vessels and capillaries in 32 cases of gastric carcinoma tissues and adjacent tissue of the tumor.
Results: Numerous lymph vessels and capillaries were seen with opened lumen in the adjacent tissues of the tumor, and fasciculated lymph capillaries were most frequent in gastric carcinoma. The maximal lumen area, perimeter and diameter of lymph vessels and capillaries in gastric carcinoma and the adjacent tissues were significantly different between metastatic group and non-metastatic group (P<0.05).
Conclusions: Dilation of lymph vessels and capillaries due to interstitial edema of the adjacent tissues of gastric carcinoma facilitates tumor metastasis, and lymph metastasis of carcinoma cells occurs through mature lymph capillaries in the adjacent tissues.
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