A comparative analysis was made of efficacy of chronic tonsillitis (CT) treatment with high frequency ultrasound (HFU), low frequency ultrasound (LFU) and laser. The study covered 172 CT patients aged 7 to 35 (65 males and 107 females) with CT history 5-32 years. Clinical examination included micropharyngoscopy, blood count, urine tests, microbiological investigation of tonsillar lacune lavage and nasal mucus, immunological tests, consultation of the therapist. Tonsillar prints were analysed for 40 patients. A compensated CT form was diagnosed in 58 patients, a decompensated one--in 114. The treatment efficacy was evaluated in the course of therapy and 1, 3, 6, 12 and 24 months after it. Immediate results were the best in patients treated with LFU on the palatine tonsils (73%). Patients exposed to LFU and laser showed good response in 35-37% in equal number of unsatisfactory outcomes. Repeated courses of all three therapies improved results in all the groups: good and satisfactory results were 69%, 51% and 43% for LFU, HFU, laser, respectively. Thus, LFU (Tonsillor device) is the most efficient up-to-date conservative therapy of CT which provides mechanical elimination of pathogens from the tonsils, a bactericidal effect, recovery of the barrier function.
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Tissue Eng Regen Med
January 2025
Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, 07804, South Korea.
Background: Exogenous Cushing's syndrome, which results from prolonged glucocorticoid treatment, is associated with metabolic abnormalities. Previously, we reported the inhibitory effect of tonsil-derived mesenchymal stem cell conditioned medium (T-MSC CM) on glucocorticoid signal transduction. In this study, we investigated the therapeutic efficacy of T-MSCs in a mouse model of exogenous Cushing's syndrome.
View Article and Find Full Text PDFBMC Rheumatol
January 2025
Department of Rheumatology, Overton Brooks VA Medical Center, Shreveport, LA, USA.
Background: Dermatomyositis is a chronic inflammatory condition affecting muscles and skin, often associated with an increased risk of cancer. Specific autoantibodies, including anti-TIF1 (Transcription Intermediary Factor 1), have been linked to this risk. We present a case of dermatomyositis in a male patient positive for anti-TIF1 antibodies, subsequently diagnosed with squamous cell carcinoma of the tonsil, a novel association not previously documented.
View Article and Find Full Text PDFHead Neck
January 2025
Department of Otorhinolaryngology - Head and Neck Surgery, Frisius Medical Center, Leeuwarden, Leeuwarden, The Netherlands.
Background: Chronic lingual tonsillitis (CLT) entails persistent inflammation of the lingual tonsils (LT), presenting in recurrent infections, throat discomfort, dyspnea, dysphagia, and LT hypertrophy.
Methods: A retrospective observational study at a nonacademic general hospital described outcomes of CLT patients undergoing base of tongue (BOT) reduction via transoral robotic surgery (TORS). Primary outcomes were changes in patient-reported quality of swallowing and life and were assessed at baseline, 3, 6, and 12 months post-TORS.
Int J Pediatr Otorhinolaryngol
January 2025
Otorhinolaryngology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt; Medicine and Surgery Program, Menoufia National University, Menoufia, Egypt. Electronic address:
Purpose: Familial Mediterranean fever (FMF) is the most prevalent genetic autoinflammatory disease worldwide. There are several novel advancements in pathophysiology, genetic testing, diagnosis, comorbidities, disease-related damage, and treatment strategies. This study aimed to assess the effect of tonsillectomy on FMF disease severity and activity.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
January 2025
Department of Otolaryngology Head and Neck Surgery, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, China.
Objective: This study aims to explore the clinical effects of simultaneous balloon eustachian tuboplasty (BET) in treating chronic secretory otitis media (COME) in children with bilateral tonsil and adenoid hypertrophy (TAH), providing a theoretical basis for the clinical application of BET.
Methods: From January 2023 to January 2024, 30 children diagnosed with COME and bilateral TAH were included in this retrospective study at our hospital. The cohort comprised a total of 55 affected ears.
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