[Morphology and electric instability of the myocardium in chronic coronary insufficiency].

Morphology and electric instability of the myocardium in patients with chronic coronary insufficiency have been studied in experiments on animals (rabbits), using a set of histological and histochemical techniques, and electron microscopy. Main aspects of myocardium reorganization at the subcellular, cellular, and tissual levels have been traced. The performed studies testify that the basic disturbances of the electric stability of the myocardium at chronic coronary insufficiency are based not upon some individual key pathogenic factor, but upon a series of alterations developing irregularly at all structural and functional levels of organization of the myocardium. That situation can be medically effectively corrected; very perspective in that respect is a targeted influence for optimizing the secretory-and-plastic function of ventricular cardiomyocytes (cardiac hystiocytes).