AI Article Synopsis
- Hydroxyapatite coatings with different crystallinities (55% for as-sprayed and 98% for vapor-flame treated) were tested in animal models to analyze their bone integration and stability.
- The as-sprayed coating showed the ability to form a bone-like apatite layer in muscle and promote new bone formation in marrow, whereas the treated coating had limited bioactivity.
- Over three months, the treated coating was more stable than the as-sprayed one, despite having weaker short-term osseointegration properties.
Article Abstract
Hydroxyapatite (HA) coating with different crystallinities were deposited by plasma spraying and vapor-flame treatment process. Their crystallinities are about 55 and 98%, respectively. These coatings were implanted in cortical bone, muscle, and marrow of dogs. The dissolution and osseointegration behavior were evaluated by scanning electron microscope (SEM) observation histological analysis. The results obtained indicated that after implanted in muscle, a bone-like apatite layer was formed on the surface of as-sprayed coating, which was not observed on the surface of the treated coating. The as-sprayed coating has the ability to induce new bone formation on its surface after implanted in marrow. In contrast, the treated coating displays a limited bone bioactivity. The vapor-flame process diminishes the short-term osseointegration properties of the HA coating, but no significant affection was found after three months implantation. Either in muscle or in cortical bone, treated coating exhibits higher stability than the as-sprayed coating, in some conditions.
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| http://dx.doi.org/10.1002/jbm.a.30323 | DOI Listing |
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