Antibacterial activity of morin and its complexes with La(III), Gd(III) and Lu(III) ions.

Acta Pol Pharm

Department of Inorganic and Analytical Chemistry, Faculty of Chemistry, Rzeszów University of Technology, 6 Powstańców Warszawy Ave., 35-011 Rzeszów, Poland.

Published: September 2005

The antibacterial activity of morin, sodium salt of morin-5"-sulfonic acid (NaMSA) and new complexes of La (II), Gd (III) and Lu (III) with morin were tested against three bacterial strains: Escherichia coli G (-), Klebsiella pneumoniae G (-), Staphylococcus aureus G (+) and compared with the activity of penicillin. All of the complexes possess inhibitory action against the tested strains. The activity of the studies compounds depends on their concentration. The complexes at a concentration of 10 microg/cylinder demonstrated higher activity than morin alone, but at a concentration of 100 microg/cylinder morin was the most effective inhibitor against the strains used in this investigation.

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