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Background: Oral food challenge tests are considered the reference standard for diagnosing food allergies; however, studies on their real-world implementation rates are limited.

Objective: The study aimed to investigate the proportion of school-age children who underwent the oral food challenge test and to understand the motivations behind food elimination and utilization of various health care services.

Methods: The questionnaire-based survey for the parents of the students who submitted the "Certificate for School Life Management (For Allergic Diseases)" was conducted across public elementary and junior high schools in Gifu prefecture, Japan.

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[Clinical diagnosis and management of wheat and buckwheat allergy: application and prospects of allergen component diagnostics].

Zhonghua Yu Fang Yi Xue Za Zhi

November 2024

Department of Clinical Laboratory of the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou510120, China.

Article Synopsis
  • - Wheat and buckwheat allergies significantly affect patients' health and well-being, with wheat allergy including various types such as food allergies and exercise-induced reactions, while buckwheat allergy is becoming more recognized in certain areas.
  • - Advanced diagnostic technologies that identify specific allergen components, like ω-5 gliadin, are enhancing the accuracy of allergy diagnosis and management, with oral challenge tests being the gold standard.
  • - Ongoing research focuses on understanding the characteristics of these allergens to improve diagnostic tools and treatment strategies, ultimately aiming to enhance patient care and quality of life, as highlighted in recent guidelines by the European Academy of Allergy and Clinical Immunology.
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: Urticaria is a common disease with a marked influence on quality of life. The key cell involved is the mast cell, which can be activated by a vast variety of stimuli, and the major mediator is histamine. Allergic urticaria is a disorder with a large variety of causes: food, drugs, insect venom, skin contact with allergens, and physical exercise.

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Article Synopsis
  • Lipid transfer protein (LTP) is a key protein linked to food-induced anaphylaxis, particularly in Mediterranean European countries, but this was the first reported case in China.
  • A 12-year-old boy in China suffered from recurrent anaphylaxis triggered by intense exercise and showed high immunoglobulin E levels sensitized to various foods and pollens, especially mugwort and multiple grains and fruits.
  • After receiving guidance on avoiding certain foods before exercise and carrying an epinephrine auto-injector, the boy experienced no further episodes over a 6-month follow-up, highlighting the need for awareness of LTP in similar cases.
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Buckwheat Allergy in Asia.

Curr Allergy Asthma Rep

September 2024

Department of Allergy, Tokyo Metropolitan Children Medical Center, Musashidai Fuchu, Tokyo, 183-8561, Japan.

Article Synopsis
  • Buckwheat (BW) allergy is a major concern in Asia, and this review focuses on three types: immediate food allergy, food-dependent exercise-induced anaphylaxis (FDEIA), and food protein-induced enterocolitis syndrome (FPIES).
  • Most research on BW allergy has been conducted in Japan and Korea, with limited studies outside of Asia, identifying key allergenic components in both common and Tartary buckwheat.
  • The review emphasizes that while general tests for immediate BW allergy have limited effectiveness, specific IgE testing for Fag e 3 and skin prick tests are valuable diagnostic tools, and calls for more comprehensive research in this area.
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