AI Article Synopsis
- * We created an Arterial Stiffness Index (ASI) to measure arterial stiffness using pulse wave patterns from blood pressure readings; this index tends to increase with age and is notably higher in women aged 50-54 compared to men.
- * The ASI was higher in individuals with multiple risk factors, especially in those who are diabetic or have hypertension, suggesting it may be a valuable tool for predicting cardiovascular events in high-risk individuals.
Article Abstract
We investigated the relation of arterial stiffness, considered an independent predictor of cardiovascular events, to cardiovascular risk factors in a population-based study of 1023 subjects. An Arterial Stiffness Index (ASI) was developed to evaluate arterial stiffness based on an analysis of the pulse wave amplitude pattern acquired from measurements of brachial blood pressure. In control subjects (n = 266) without any major risk factors, the ASI was 46 +/- 11, and increased with age (r = 0.346). The ASI was significantly higher in women ranging from 50 to 54 years of age than in age-matched men. The ASI rose in correlation with the number of risk factors. Subjects with two risk factors showed a significantly higher ASI than those without any risk factors (54 +/- 26 vs. 46 +/- 11). The ASI was significantly increased in diabetic subjects with hypertension in comparison to those without hypertension. Furthermore, hyperlipidemic subjects with hypertension showed significantly higher values than those without hypertension. ASI could be a useful predictor of cardiovascular events in hypertensive subjects with multiple risk factors.
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| http://dx.doi.org/10.5551/jat.12.175 | DOI Listing |
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