We report two cases of very rare congenital hypoplastic anemia (Diamond-Blackfan anemia) in children. Both patients were boys admitted to our Clinic as severe anemia of unknown etiology, and had been previously treated in their Cantonal hospitals. Diagnose of congenital hypoplastic anemia was set up according: anamnesis, clinical picture with dominant features of anemia, cytomorphologic finding of peripheral blood picture, according blood marrow aspirate finding and according erithropoetin level level in blood.
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