[Phyllodes tumor of the breast: analysis of 8 patients].

J Gynecol Obstet Biol Reprod (Paris)

Département de Gynécologie, Hôpital Jeanne-de-Flandre, 2, avenue Oscar-Lambret, 59037 Lille Cedex.

Published: May 2005

Introduction: Phyllodes tumors of breast are rare and usually benign. These are histologically fibro-epithelial tumors similar to fibroadenomas. Histological confirmation on the operative specimen is required to establish the diagnosis and histological pronostic of phyllode tumors.

Materials And Methods: We reviewed 8 cases of phyllodes tumors and the literature to report the circumstances of occurrence of these tumors, and their specific clinical diagnosis, therapeutic, prognostic features.

Results: 62.5% of patients were nulliparous. The mean age at diagnosis was 33.4 years. Mean tumor size was 3.75 cm. Tumours predominated on the right side (87.5%) and upper-outer quadrant (62.5%). Imaging findings were helpful for diagnosis. Aspiration cytology demonstrated the phyllode tumor in 43% of patients. Wide tumorectomy was performed in seven patients. One patient underwent mastectomy and radiotherapy and chemotherapy. The recurrence rate (37.5%) justifies wide margin excision. There were no deaths in our series.

Discussion: and conclusion. These results together with those reported in the literature show that the loco-regional and general spread depends on margin surgery.

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http://dx.doi.org/10.1016/s0368-2315(05)82743-7DOI Listing

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