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Article Synopsis
  • Discogenic low back pain (DLBP) is challenging to diagnose, but full endoscopic spinal surgery with thermal annuloplasty has shown good results in treating refractory cases, as demonstrated in a report of a 22-year-old female patient.
  • After a series of treatments, including discectomy and injections, it was found that a residual high-intensity zone (HIZ) was contributing to her persistent pain.
  • The application of thermal annuloplasty effectively alleviated her low back pain by targeting inflammation associated with the HIZ, marking a potentially innovative approach for managing postoperative DLBP.
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Does the high-intensity zone of lumbar intervertebral disc at magnetic resonance imaging have diagnostic value for discogenic low back pain? A meta-analysis.

BMC Musculoskelet Disord

October 2024

Department of Orthopedics III, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 5 Haiyun Warehouse, Dongcheng District, Beijing, 100700, China.

Article Synopsis
  • The study investigates the relationship between high-intensity zones (HIZ) in MRI scans of lumbar discs and discogenic low back pain (DLBP), aiming to clarify their diagnostic relevance.
  • A systematic review of 25 studies involving nearly 5,900 patients found that while HIZ shows moderate sensitivity (49%) for identifying DLBP, it has high specificity (89%).
  • The authors conclude that while HIZ can be a useful diagnostic tool for DLBP, more high-quality research is required to solidify these findings.
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Mechanical influence of facet tropism in patients with chronic discogenic pain disorder.

Bone Joint Res

September 2024

Department of Physical Medicine and Rehabilitation, Korea University Guro Hospital, Seoul, South Korea.

Article Synopsis
  • The study evaluated how facet tropism (an abnormal curvature of spinal joints) affects chronic lumbosacral disc pain by analyzing clinical data and computer simulations (FEM).
  • A retrospective analysis of 318 spinal levels in 156 patients revealed that facet tropism significantly predicts positive outcomes in discography, with notable biomechanical impacts on disc stress and displacement in affected areas.
  • The results suggest that facet tropism can lead to higher risks of disc herniation and degeneration due to changes in pressure and increased mechanical stress on the discs.
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Article Synopsis
  • Percutaneous lumbar nucleoplasty (PLN) and intradiscal electrothermal therapy (IDET) are both effective treatments for discogenic low back pain (D-LBP), with PLN showing better results.
  • In a study of 205 patients, 60.5% reported at least 50% pain relief after 6 months, with higher success rates noted for PLN compared to IDET.
  • Factors such as a high-grade Modified Dallas Discogram and treatment at the L3/L4 spinal level predicted better outcomes, while coexisting psychiatric disorders negatively affected treatment success.
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Lumbar intervertebral disc degeneration in low back pain.

Minerva Anestesiol

April 2024

Division of Pain Medicine, Department of Anesthesiology and Pain Medicine, Clinical Learning, Evidence And Research (CLEAR) Center for Musculoskeletal Research, University of Washington School of Medicine, Seattle, WA, USA -

Article Synopsis
  • Intervertebral disc degeneration involves damage to the structure and function of the discs in the spine, which can lead to low back pain due to nerve activation.
  • This review discusses how degeneration symptoms are linked to pain, focusing on various biological mechanisms behind degeneration, such as changes in cell function and stress factors.
  • Current diagnoses for disc-related pain often lack accuracy, and treatments tend to address general low back pain rather than specifically targeting discogenic pain, highlighting the need for more precise research on the molecular causes of pain.
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