Gonadotropin releasing hormone (GnRH) occurs in various isoforms in mammals, i.e. GnRH-I (mammalian GnRH), GnRH-II (chicken GnRH-II), GnRH-III (salmon GnRH) and two forms of lamprey GnRH. The function of the latter four molecules have only been partially investigated. Also not much is known about the physiological effects of GnRH-I immunization on the function of these GnRH isoforms. In order to avoid possible harmful side-effects due to undesired neutralization of GnRH isoforms, GnRH-I specificity of antibodies raised against a panel of alternative GnRH antigens was determined. The results show that GnRH antigens can be designed which generate antibodies that specifically bind GnRH-I, without cross-reacting with other GnRH isoforms.
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Molecular response of canine testis to GnRH agonist: Insights into AR, HIF-1α, and HSPs expression during arrest and recovery of spermatogenesis.
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Unit for Reproductive Medicine - Clinic for Small Animals, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany. Electronic address:
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- Slow-release GnRH agonist implants are used in male dogs for contraception, and their effects are reversible, although safety concerns exist.
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Fishing for the gonadotropin releasing hormone from the genome of Salminus brasiliensis (Characiformes: Bryconidae).
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Universidade Federal de São João Del Rei - UFSJ, Laboratório de Recursos Genéticos, Programa de Pós-graduação em Biotecnologia, São João Del Rei, MG, Brasil.
The technological development of tools that enable the spawning of different native species is paramount to enable ex situ conservation initiatives, as well as providing means for commercial hatchery of threatened fish which, in turn, relieve fisheries pressure over wild stocks. Neotropical migratory freshwater fish depend on hormonal induction for spawning in hatcheries, through expensive methods of limited efficiency. Salminus brasiliensis is one of the largest Neotropical freshwater fish, a piscivorous top-predator, prized in angling, highly valued in the market, and appreciated in gastronomy.
View Article and Find Full Text PDFGenome-wide identification of Gα family in grass carp (Ctenopharyngodon idella) and reproductive regulation functional characteristics of Cignaq.
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Fisheries College, Hunan Agricultural University, Changsha, 410128, China.
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Nitric oxide mediated kisspeptin regulation of steroidogenesis and gametogenesis in the catfish, Clarias batrachus.
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Centre for Neuroendocrinology, Department of Immunology, University of Pretoria, Pretoria, South Africa.
Nitric oxide (NO) is a gaseous molecule that regulates various reproductive functions. It is a well-recognized regulator of GnRH-FSH/LH-sex steroid secretion in vertebrates including fish. Kisspeptin is a recently discovered neuropeptide which also regulates GnRH secretion.
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