The objective of this longitudinal study of 41 Swedish men with HIV disease was to assess what variables or combination of variables might predict loss to retention at 12 months. The variables of focus were of patients' characteristics, quality of life, psychological, and medical characters. It appears that it is psychological variables relating to coping with HIV disease that are the best predictors of failure to retain respondents in this cohort. The responses to two items: 'I have been doing things that I believe will improve my health (e.g. changed my diet)' and 'I feel like giving up' correctly classified over 85% of cases lost to the study. These findings are worthy of replication and may prove useful in maximizing retention rates in longitudinal studies of the course of HIV disease and medication adherence and outcome.
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