The bio-trickling filter packed with ZX02 stuffing is used to treat the mix gases containing butyl acetate, n-butyl alcohol and phenylacetic acid(BBP), which are discharged from Penicillin workshop of Pharmaceutical Factory. The reactor was operated for 110 days to investigate the effect of influent load, retention time and spray water on the removal of BBP and the biodegradation characteristics. The reactor displayed preferential utilization of BBP, when the maximum influent load of BBP were 229.5g/(m3 x h), 275.4 g/(m3 x h) and 42.5g/(m3 x h), the removal efficiencies were 96%, 95% and 100% respectively. The results show that the bio-trickling filter can effectively treat the mix gases and the optimum parameters were as followed: retention time was 31.2 s, the volume of spray water was 4 L/(L x d). The bio- trickling reactor has strong ability to resist shock of high influent load and resistance is maintained at low value, what's more, it doesn't need to carry out back washing frequently. With all these advantages it can be operated steadily for long time.

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