The Authors present the results of a multidisciplinary study carried out on a sample of 103 children comprised in a programme of vaccination against Streptococcus pneumoniae infections, in order to avoid the worsening of their asthma. In the nasopharyngeal exudate of 39 children, we detected the presence of S. pneumoniae strains of serotypes 6, 8, 14, and 19 and their absence after vaccination with PNEUMO 23. This was followed by a significant decrease in the incidence of pneumococcal infections and also by the reduction in the frequency of crises and severity of the disease.

Download full-text PDF

Source

Publication Analysis

Top Keywords

streptococcus pneumoniae
8
[epidemiologic clinical
4
clinical laboratory
4
laboratory observations
4
observations streptococcus
4
pneumoniae serotypes
4
serotypes implicated
4
implicated evolution
4
evolution asthma
4
asthma children]
4

Similar Publications

Purpose: Cost-utility analyses examining the value of new vaccines for pneumococcal disease will require health state utilities as inputs. Existing utilities for pneumococcal infections in young children are limited. The purpose of this study was to estimate health state utilities associated with pneumococcal infections in young children.

View Article and Find Full Text PDF

Gut microbiota mediated T cells regulation and autoimmune diseases.

Front Microbiol

December 2024

Laboratory of Anti-allergic Functional Molecules, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.

Gut microbiota regulates the immune system, the development and progression of autoimmune diseases (AIDs) and overall health. Recent studies have played a crucial part in understanding the specific role of different gut bacterial strains and their metabolites in different AIDs. Microbial signatures in AIDs are revealed by advanced sequencing and metabolomics studies.

View Article and Find Full Text PDF

Endometritis is one of the main reproductive disorders in mares and due to the increasing prevalence of antibiotic resistance, the use of probiotics in the prevention and treatment of endometritis in mares has gained interest, given their potential to restore and maintain a healthy uterine microbiota. Therefore, the aim of this study was to evaluate the antimicrobial properties of total metabolites of Lactobacillus acidophilus (LA) and Lactiplantibacillus plantarum (LP) against common equine endometrial pathogenic bacteria in vitro (Acinetobacter baumannii, Escherichia coli (1), Escherichia coli (2), Escherichia coli (3), Escherichia coli (4), Enterobacter cloacae, Streptococcus equi, Staphylococcus warneri, Actinobacillus equi and Klebesiella pneumoniae), as well as to assess their low molecular weight metabolites (loM) and extracellular vesicle (EVs) inhibition capacity over a multidrug-resistant E. coli isolated from mares with clinical endometritis.

View Article and Find Full Text PDF

Diabetes impairs IFNγ-dependent antibacterial defense in the lungs.

Mucosal Immunol

December 2024

Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany; German center for lung research (DZL), Augustenburger Platz 1, 13353 Berlin, Germany. Electronic address:

Diabetes mellitus is associated with an increased risk of pneumonia, often caused by so-called typical and atypical pathogens including Streptoccocus pneumoniae and Legionella pneumophila, respectively. Here, we employed a variety of mouse models to investigate how diabetes influences pulmonary antibacterial immunity. Following intranasal infection with S.

View Article and Find Full Text PDF

Nasopharyngeal transmission of Streptococcus pneumoniae is a prerequisite for the development of pneumococcal diseases. Previous studies have reported a relationship between respiratory viruses and S. pneumoniae infections.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!