Objective: To determine the susceptibilities of M. tuberculosis H37Ra and M. chelonei subsp. absecessus to several frequently-used disinfectants and to evaluate the practicability of surrogating M. tuberculosis by the latter.
Methods: A suspension quantitative bactericidal test was set up in accordance with Chinese Technique Standard for Disinfection to evaluate the susceptibility of each mycobacteria strain to each selected disinfectant. Killing log value was used as criterion in comparing the susceptibility to disinfectants between the two strains.
Results: M. chelonei subsp. abscessus was more resistant to chlorine disinfectant than M. tuberculosis while the two strains were similarly resistant to iodophor disinfectant, peracetic acid, alcohol and glutaraldehyde disinfectant.
Conclusion: M. chelonei subsp. abscessus has the potential to surrogate M. tuberculosis in evaluating mycobactericidal efficacies of disinfectants.
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Biomed Res Int
March 2016
Department of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Tongzhou District, Beijing 101149, China.
Purpose of this paper is to analyze different species' proportion of nontuberculosis mycobacteria (NTM) and susceptibility to clarithromycin of different species. 278 clinical NTM isolates were identified into species by using 16S rRNA, rpoB and hsp65. Then clarithromycin susceptibility testing against different species was done separately, using microplate Alamar Blue assay.
View Article and Find Full Text PDFBiomed Environ Sci
April 2005
Department Medical Technology, Huaxi School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China.
Objective: To determine the susceptibilities of M. tuberculosis H37Ra and M. chelonei subsp.
View Article and Find Full Text PDFEur J Gastroenterol Hepatol
December 1995
Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Objective: In addition to Mycobacterium paratuberculosis, other slow-growing as well as rapid-growing mycobacteria were isolated from mucosa or full thickness samples of intestine from patients with Crohn's disease. The meaning of these data remained unclear. To investigate the possible aetiological role of these rapid- and slow-growing mycobacteria, serosa and mesenteric lymph nodes were also cultivated in the present study.
View Article and Find Full Text PDFAntimicrob Agents Chemother
July 1993
Unité de la Tuberculose et des Mycobactéries, Institut Pasteur, Paris, France.
The antimycobacterial spectrum of roxithromycin, a semisynthetic 14-membered ring macrolide, was determined against 28 strains belonging to 16 species of atypical mycobacteria by measuring radiometric MICs by BACTEC methodology at two different pH values, i.e., 6.
View Article and Find Full Text PDFKekkaku
May 1993
National Hiroshima Hospital, Higashihiroshima City, Japan.
Purified protein derivatives (PPDs) prepared from M. intracellulare (PPD-B), M. kansasii (PPD-Y), M.
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