Background: Ultrasonography has provided the means for objective and non-invasive monitoring of the dynamics of some skin diseases. The pathologic scars (keloids and hypertrophic scars) that have an increased content of collagen, and have been not analyzed by high-frequency ultrasound so far. The purpose of the present study was to determine the ecographic features of these scars with a view in developing a reliable method for assessing the effectiveness of different therapeutic approaches.
Methods: Six pathological scars from five patients were examined by a 20 MHz B-Scanner and compared with healthy skin of the same region. Densitometry analysis was performed with the aid of a dedicated software.
Results: All the pathologic scars studied showed an easily identified echo-poor image clearly demarcated from the surrounding not involved tissue. When they were analyzed by densitometry, the lesions had highly significant reduced densitometric values (7.6+/-4.7) compared with regional healthy skin (31.79+/-10.8).
Conclusion: The high-frequency ultrasonography is a suitable objective and non-invasive method for discriminating healthy from pathologic skin in hypertrophic scars and keloids.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1600-0846.2005.00118.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association Between Cesarean Scar and Pelvic Floor Muscle Tone at 6-8 Weeks Postpartum.
Int Urogynecol J
January 2025
Department of Rehabilitation Medicine, First Affiliated Hospital of Gannan Medical University, No. 128 Jinling Road, Zhanggong District, Ganzhou City, 341000, Jiangxi Province, China.
Introduction And Hypothesis: The relationship between cesarean section scars and active pelvic floor muscle tone lacks sufficient evidence. This study is aimed at investigating the relationship between the severity of cesarean section scars and active pelvic floor muscle tone in postpartum women.
Methods: We conducted a prospective cross-sectional study of 604 women at 6-8 weeks postpartum.
Comparing the Efficacy of Triamcinolone Acetonide Versus Bleomycin in Hypertrophic Scars in Burn Patients: A Clinical Trial.
Med J Islam Repub Iran
September 2024
Burn Research Center, Shahid Motahari Hospital, Iran University of Medical Sciences, Tehran, Iran.
Background: Treatment of hypertrophic burn scars is challenging. Intralesional injection of corticosteroids has been the first line of treatment. Triamcinolone Acetonide (TA) and Bleomycin (BLE) are standard therapeutic options.
View Article and Find Full Text PDFEvaluation of the efficacy, safety, and satisfaction rate of topical latanoprost in patients with hypopigmented burn scars treated with fractional CO2 laser: a double-blind randomized controlled clinical trial.
Lasers Med Sci
January 2025
Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Niayesh Street, Sattar Khan Avenue, Rasool Akram Hospital, Tehran, Iran.
Burn scars present psychological and social challenges for patients, classified into atrophic and hypertrophic types. Treatments like corticosteroid injections, laser therapy, and platelet-rich plasma (PRP) injections are commonly recommended for hypertrophic scars, while regenerative medicine and fractional CO2 lasers are linked to some degree of improvement for atrophic scars. Hypopigmented and depigmented burn scars pose ongoing challenges for healthcare providers and patients, with therapies such as intense pulsed light and fractional CO2 laser showing variable effects in treating these conditions.
View Article and Find Full Text PDFEndoscopic Flexor Hallucis Longus Tendon Transfer for the Treatment of Chronic Achilles Tendon Defects.
JBJS Essent Surg Tech
January 2025
The Ohio State University College of Medicine, Columbus, Ohio.
Background: An all-inside endoscopic flexor hallucis longus (FHL) tendon transfer is indicated for the treatment of chronic, full-thickness Achilles tendon defects. The aim of this procedure is to restore function of the gastrocnemius-soleus complex while avoiding the wound complications associated with open procedures.
Description: This procedure can be performed through 2 endoscopic portals, a posteromedial portal (the working portal) and a posterolateral portal (the visualization portal).
Slit1 Promotes Hypertrophic Scar Formation Through the TGF-β Signaling Pathway.
Medicina (Kaunas)
December 2024
Department of Rehabilitation Medicine, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, 94-200 Yeongdeungpo-Dong, Yeongdeungpo-Ku, Seoul 07247, Republic of Korea.
Slit1 is a secreted protein that is closely related to cell movement and adhesion. Few studies related to fibrosis exist, and the preponderance of current research is confined to the proliferation and differentiation of neural systems. Hypertrophic scars (HTSs) are delineated by an overproduction of the extracellular matrix (ECM) by activated fibroblasts, leading to anomalous fibrosis, which is a severe sequela of burns.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!