Objective: To perform spatial analysis on dengue transmission in a medium-sized city in the interior of the State of São Paulo, Brazil, covering the period from September 1990 to August 2002.
Methods: Autochthonous cases with confirmation by laboratory tests were utilized. Population data on the city of São José do Rio Preto were obtained from the Brazilian Institute for Geography and Statistics and the municipal authorities. The cases were georeferenced according to street addresses and clustered according to the 432 census tracts in the municipality, thus resulting in thematic maps.
Results: A rising trend in annual incidence was noted, with a peak in 2000/2001. From 1990 to 1994 the length of the transmission period reached a maximum of five months per year. This period increased in length over subsequent years. In the final year investigated, transmission occurred in all twelve months, without interruptions. Analysis of the period of highest incidence showed that the transmission did not occur uniformly. While 29% of the tracts registered incidences of less than 1,000 cases per 100,000 inhabitants, 5% of them had more than 5,000 cases.
Conclusions: A process of increasing endemicity was observed, with transmission throughout the year, without the need for virus introducers. The endemic characteristic of the transmission and the differentiated occurrence according to areas need to be taken into account when developing strategies for dengue control.
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http://dx.doi.org/10.1590/s0034-89102005000300016 | DOI Listing |
BMC Infect Dis
January 2025
Yunnan Institute of Endemic Diseases Control and Prevention, Yunnan Provincial Key Laboratory for Zoonosis Control and Prevention, Dali, Yunnan, 671000, China.
Background: Yunnan Province, located in the southwestern part of China and neighboring endemic dengue regions of Southeast Asia, has experienced annual autochthonous outbreaks of dengue fever from 2013 to 2023. This study examines the epidemiological and spatiotemporal clustering characteristics of dengue within the province.
Methods: Descriptive epidemiological methods were used to analyse outbreak characteristics.
PLoS Negl Trop Dis
January 2025
Division of Vector Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.
Mosquito-transmitted viruses such as dengue are a global and growing public health challenge. Without widely available vaccines, mosquito control is the primary tool for fighting the spread of these viruses. New mosquito control technologies are needed to complement existing methods, given current challenges with scalability, acceptability, and effectiveness.
View Article and Find Full Text PDFiScience
January 2025
Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique, Laval, Québec H7V 1B7, Canada.
During infection, dengue virus (DENV) and Zika virus (ZIKV), two (ortho)flaviviruses of public health concern worldwide, induce alterations of mitochondria morphology to favor viral replication, suggesting a viral co-opting of mitochondria functions. Here, we performed an extensive transmission electron microscopy-based quantitative analysis to demonstrate that both DENV and ZIKV alter endoplasmic reticulum-mitochondria contact sites (ERMC). This correlated at the molecular level with an impairment of ERMC tethering protein complexes located at the surface of both organelles.
View Article and Find Full Text PDFOpen Forum Infect Dis
January 2025
Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Background: Arboviruses, including Dengue (DENV), Zika, and chikungunya, cause recurrent outbreaks of varying intensity in tropical countries. This study aimed to investigate other arboviruses, including Zika and chikungunya, in patients clinically suspected of Dengue and to characterize the circulating Dengue serotypes and genotypes in Northern Vietnam from 2020 to 2022. To date, information on this topic in the region has been limited.
View Article and Find Full Text PDFBMC Infect Dis
January 2025
College of Medicine, Federal University of Vale do São Francisco-UNIVASF, Petrolina, Pernambuco, 56304-917, Brazil.
Background: Human activities, such as urbanization and climate change, have facilitated the spread of arbovirus-carrying vectors, disproportionately affecting vulnerable traditional Indigenous communities.
Objective: To explore the relationships between subclinical myocardial dysfunction, assessed by global longitudinal strain (GLS), and comprehensive arbovirus serology in an Indigenous population, while also describing the serological and epidemiological profile of dengue, chikungunya, and Zika viruses.
Methods: This ancillary study is part of the first phase (2016-2017) of the Project of Atherosclerosis among Indigenous Populations (PAI), a cross-sectional study involving participants from two Indigenous communities with different degrees of urbanization and a highly urbanized city in Northeast Brazil.
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