Objective: Non-recognition of alcohol problems in medical and surgical patients may have adverse consequences. This may be minimised by having a high index of suspicion and the use of screening instruments.
Patients And Methods: Items from two alcohol abuse screening instruments (CAGE and Patient Health Questionnaire) were administered on medical and surgical in-patients in a general hospital during a one-year period, to determine the prevalence of alcohol use and abuse.
Results: The prevalence of alcohol use was 49.8% and for alcohol abuse 14.8%. Paternal alcohol use and cigarette smoking were found to be good indicators of alcohol abuse.
Conclusion: Detailed inquiry about alcohol use, looking for indices of cigarette smoking and routine use of screening instruments should assist in discovering many patients with alcohol abuse who probably would have denied having the problem.
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Int J Mol Sci
January 2025
Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Alcohol is the second-most misused substance after tobacco. It has been identified as a causal factor in more than 200 diseases and 5.3% of all deaths and is associated with significant behavioral, social, and economic difficulties.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Legal Medicine, Department of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, 95123 Catania, Italy.
Fentanyl is a synthetic opioid widely used for its potent analgesic effects in chronic pain management and intraoperative anesthesia. However, its high potency, low cost, and accessibility have also made it a significant drug of abuse, contributing to the global opioid epidemic. This review aims to provide an in-depth analysis of fentanyl's medical applications, pharmacokinetics, metabolism, and pharmacogenetics while examining its adverse effects and forensic implications.
View Article and Find Full Text PDFInt J Environ Res Public Health
January 2025
Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
To address the holistic and continuity of care needs of people who attend North East hospitals frequently for alcohol-related reasons, Recovery Navigator (Navigator) roles were introduced into Alcohol Care Teams in six hospitals in the North East of England, UK, in 2022. The Navigators aimed to provide dedicated holistic support to patients experiencing alcohol harms, starting whilst in the hospital with the potential to continue this beyond discharge. This qualitative study explores the contributions that the Navigators make towards integrated alcohol care.
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January 2025
Faillace Department of Psychiatry and Behavioral Sciences, UTHealth McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
Cocaine use disorder (CUD) is associated with executive functioning impairments linked to serotonergic function. Previous studies reported efficacy with the selective serotonin reuptake inhibitor citalopram in reducing cocaine use. The current study explored moderation and mediation of citalopram effects on cocaine use by performance across executive function domains.
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January 2025
Department of Psychological Sciences, Western Kentucky University, Bowling Green, KY, USA.
Despite available and effective prevention and treatment strategies for substance use disorders (SUD), drug overdose deaths in the US remain high. Further, limited public knowledge of SUD pharmacotherapies may contribute to increased stigmatization toward SUD medications and a lack of willingness to help people with SUD. This study evaluated knowledge and attitudes about SUD pharmacotherapies and willingness to help people with SUD among a sample of U.
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