A 12-year-old intact male mongrel dog with a weight of 22 kg was referred with a complaint of progressive tetraparesis. Cervical myelography revealed an intradural-extramedullary mass at the second cervical vertebra. After computed tomography (CT) under general anesthesia, the patient showed dyspnea and cyanosis caused by insufficient movement of the chest wall. Positive pressure ventilation was therefore initiated. Hemilaminectomy and partial mass removal were performed 12 hr after the CT. The mass was histopathologically diagnosed as meningioma. Gradual weaning from the mechanical ventilation lasted for 80 hr after the operation. The patient eventually recovered from the ventilatory failure and the tetraparesis at approximately 6 and 14 days after the operation, respectively.
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http://dx.doi.org/10.1292/jvms.67.599 | DOI Listing |
Eur J Pediatr
January 2025
Hospital de Clinicas de Porto Alegre, Rua Silva Jardim 1155 # 701, Porto Alegre, RS, 90450-071, Brazil.
Unlabelled: To evaluate the accuracy of the lung ultrasound score (LUS) in predicting ventilatory weaning failure during neonatal hospitalization in the NICU and to identify factors associated with weaning failure, including corrected gestational age (CGA). This prospective, longitudinal, pragmatic and observational cohort study included neonates on mechanical ventilation for at least 48 h. The primary outcome was the accuracy of lung ultrasound in predicting 3-day weaning failure, with the ROC curve used to determine the best LUS cutoff (sensitivity and specificity).
View Article and Find Full Text PDFESC Heart Fail
January 2025
Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Berlin, Germany.
Aims: Patients with heart failure with preserved ejection fraction represent half of the heart failure patients nowadays, an at least steady trend due to the aging of the population. We investigated whether the parameters obtained from cardiopulmonary exercise testing (CPET) correlated with the prognosis of these patients. This prospective observational cohort study assesses the relationship between the CPET parameters peakVO and VE/VCO slope and the number of heart failure hospitalizations or cardiovascular death of these patients.
View Article and Find Full Text PDFPeerJ
January 2025
Department of Emergency Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Background: Acute lung injury (ALI) is a disordered pulmonary disease characterized by acute respiratory insufficiency with tachypnea, cyanosis refractory to oxygen and diffuse alveolar infiltrates. Despite increased research into ALI, current clinical treatments lack effectiveness. Tetramethylpyrazine (TMP) has shown potential in ALI treatment, and understanding its effects on the pulmonary microenvironment and its underlying mechanisms is imperative.
View Article and Find Full Text PDFS D Med
October 2024
Department of Surgery, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
A hamartoma is a benign tumor of tissue resembling the site of origin, despite exhibiting disorganized architecture. While benign, symptoms typically arise from mass effects. They are often found in the lower gastrointestinal tract and are a rare finding in the pharynx and larynx.
View Article and Find Full Text PDFJ Neurol
January 2025
Centre de Génétique Humaine, Centre Hospitalier Universitaire de Besançon, Besançon, France.
Introduction: The MAPT gene encodes Tau, a protein mainly expressed by neurons. Tau protein plays an important role in cerebral microtubule polymerization and stabilization, in axonal transport and synaptic plasticity. Heterozygous pathogenic variation in MAPT are involved in a spectrum of autosomal dominant neurodegenerative diseases known as taupathies, including Alzheimer's disease, Pick's disease, fronto-temporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
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