Aims: Animal experimentation often demonstrates that alcohol leads to disinhibited behaviour, such as increased aggression, increased social behaviour, or increased impulsivity. However, human experimentation demonstrates that alcohol can have either disinhibiting or inhibiting effects on behaviour, depending on salient environmental cues. Our aim was to illustrate how alcohol myopia theory could be applied to the literature assessing the effects of alcohol on behaviour in animals.
Methods: The effects of alcohol on animal behaviour were reviewed in several domains, including aggression, social behaviours, and impulsivity. Suggestions for testing alcohol myopia with animal research paradigms were provided.
Results: Current animal research paradigms are often designed in such a way that alcohol myopia cannot be tested. To test alcohol myopia, we recommend manipulating the salience of both impelling and inhibiting environmental cues.
Conclusions: Disinhibition alone cannot explain alcohol's effects on behaviour. We contend that alcohol myopia theory helps to explain some contradictory findings in the human and animal literature. We encourage animal researchers to develop research paradigms to provide tests of alcohol myopia.
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http://dx.doi.org/10.1093/alcalc/agh177 | DOI Listing |
Memory
January 2025
Department of Psychology, University of Portsmouth, Portsmouth, UK.
Many witnesses are intoxicated at crime scenes, yet little is known of their ability to accurately describe perpetrators to police. We therefore explored the impact of alcohol on delayed verbal face recall across two experiments. Participants were administered an alcoholic or non-alcoholic beverage prior to viewing either one or two unfamiliar female faces, which they described from memory the following day while in a sober state.
View Article and Find Full Text PDFExp Eye Res
December 2024
Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, 200031, China; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, 200031, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, Shanghai, 200031, China. Electronic address:
This study compares the physicochemical properties of corneal stromal lenticules following decellularization via four methods. Human corneal stromal lenticules, derived from small incision lenticule extraction surgery, underwent decellularization with sodium dodecyl sulfate (SDS), Triton X-100 (Tx) combined with SDS, trypsin-ethylenediaminetetraacetic acid (TE), or NaCl combined with deoxyribonuclease (DNase), respectively. Lenticule DNA and glycosaminoglycan (GAG) content, immunofluorescence staining of cell nuclei and collagen, transparency, biomechanics, histological structure, and immunogenicity were examined in each group and compared with fresh lenticules.
View Article and Find Full Text PDFChemistry
December 2024
Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK.
Eur J Ophthalmol
August 2024
Miranza Begitek, Donostia-San Sebastián, Spain.
J Stud Alcohol Drugs
August 2024
Department of Psychology, University of Tennessee-Knoxville - Knoxville, TN.
Objective: Sexual and gender diverse (SGD) individuals are at heightened risk for intimate partner aggression (IPA) perpetration relative to their heterosexual and cisgender peers. Alcohol is a well-established cause of IPA perpetration in cisgender, heterosexual couples; however, minimal research has investigated the alcohol-IPA perpetration link in SGD couples. The relative lack of work in this area is a major barrier to addressing this health disparity.
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