Bicarbonate stimulates the activities of several class III adenylyl cyclases studied to date. However, we show here that bicarbonate decreased V(max) and substrate affinity in Cya1, a major adenylyl cyclase in the cyanobacterium Synechocystis sp. strain PCC 6803. This indicates that manifestation of the bicarbonate responsiveness is specifically modulated in Cya1.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1169521 | PMC |
| http://dx.doi.org/10.1128/JB.187.14.5032-5035.2005 | DOI Listing |
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