We report a case of E. coli meningitis presented initially without nuchal rigidity. Despite intensive care treatment, CSF was not sterilized and the patient died at 17 days after his admission. Patients with an unexplained altered sensorium with fever should undergo LP to evaluate for this rare entity and to direct early antimicrobial treatment which possesses efficacy for meningeal infection.
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Antibiotics (Basel)
November 2024
Microbiology and Diagnostic Immunology Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Background: Infant meningitis, particularly caused by , remains a life-threatening condition, especially in premature and low-weight infants. Infections of the central nervous system can be fatal, necessitating prompt diagnosis and appropriate treatment. Acute infections caused by various pathogens, including , often present with similar clinical symptoms.
View Article and Find Full Text PDFClin Microbiol Infect
December 2024
Department of Paediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Objectives: We aimed to study the association between early-onset neonatal infection in near-term and term children and school performance based on mandatory tests in reading and mathematics.
Methods: We conducted a nationwide register-based cohort study including all Danish near-term and term singletons born from 1997 to 2009. Early-onset infection was defined as an invasive bacterial infection during the first week of life.
Medicine (Baltimore)
December 2024
University of Pennsylvania, Philadelphia, PA.
Bacterial meningitis causes significant morbidity and mortality in infants. Lumbar punctures are often deferred until the results of blood cultures are known and sometimes not considered, making this population susceptible to a missed diagnosis. There are few studies describing the epidemiology of neonatal meningitis in quaternary neonatal intensive care unit settings.
View Article and Find Full Text PDFVet Med Sci
January 2025
Department of Chemistry, Mbarara University of Science and Technology, Mbarara, Uganda.
Dog bites are a source of zoonotic infections to humans, such as pasteurellosis and meningitis. Zoonotic bacterial identification and their antibiotic susceptibility assessment are key towards the successful management of such infections. This study isolated and identified zoonotic bacterial species from the oral cavities of indigenous dogs and also determined their antibiotic susceptibility profile.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Master Program in Biomedical Sciences, School of Medicine, Tzu Chi University, No. 701, Sec. 3, Zhongyang Road, Hualien 97004, Taiwan.
Bacteriophages are viruses that have the potential to combat bacterial infections caused by antimicrobial-resistant bacterial strains. In this study, we investigated a novel lytic bacteriophage, vB_EcoS_JSSK01, isolated from sewage in Hualien, Taiwan, which effectively combats multidrug-resistant (MDR) of the K1 capsular type. K1 is a major cause of severe extraintestinal infections, such as neonatal meningitis and urinary tract infections.
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