Background: Portable recording devices without electroencephalogram recordings are frequently used for diagnosis of sleep-disordered breathing. However, an exact measure of sleep is important, since the diagnosis is based on the average number of events per hour of sleep, the apnea/hypopnea index (AHI). Actimetry is a simplified method for distinguishing sleep and wakefulness by measurements of activity.
Objectives: In this study, recording with a portable recording device (Reggie) including an incorporated actimeter and polysomnography were done simultaneously in order to test the effect of the actimeter.
Methods: The study was performed at the sleep-related breathing disorder unit at the Ullevaal University Hospital, Oslo, Norway. Fifty-two consecutive patients referred to the hospital for diagnosis of sleep-disordered breathing were included.
Results: There is agreement between the AHI obtained from the polysomnography and the AHI obtained from the Reggie system. The estimated mean difference is 3.5, with an SD of 5.3 (r = 0.98). The sleep time calculated with the Reggie system is greater than the sleep time obtained by polysomnography, the mean difference being 46 min, SD 56 min (r = 0.45).
Conclusions: Sleep time calculations with the Reggie system overestimate the sleep time. Still, the AHIs obtained by the two systems show good agreement. There is a slight tendency for the Reggie system to provide an AHI which is too low. This difference is small, and in most cases, it will be of no clinical significance.
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http://dx.doi.org/10.1159/000086722 | DOI Listing |
Eye (Lond)
November 2021
Department of Neuro-ophthalmology, Departments of Ophthalmology and Neurology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA.
Purpose: To determine if the presence or absence of retinal and choroidal folds on SD-OCT imaging can distinguish between mild papilloedema and pseudopapilledema.
Design: Cross-sectional cohort study METHODS: Subjects with optic disc elevation (Frisen grades 1 and 2 only) were eligible to be enrolled prospectively. Pseudopapilledema was defined as a lack of change in optic disc appearance between two visits <6 months apart, and papilloedema was defined as change in optic disc appearance between two visits <6 months apart determined by review of fundus photographs by a masked neuro-ophthalmologist.
Spectrochim Acta A Mol Biomol Spectrosc
June 2020
Chemistry Department, U.S. Naval Academy, Annapolis, MD 21402, USA.
The infrared (IR) spectrum of dipropargyl ether, (HC≡C-CH)O, has been reinvestigated for the compound's liquid, amorphous, and crystalline forms. The IR baseline changes and bandshape distortions seen in literature spectra have been considerably reduced by a different choice of conditions for preparing the crystalline solid, leading to the discovery of two crystalline phases of the ether. A spectrum of the liquid phase has been recorded and compared to that of the amorphous ether to check for possible procedural artifacts.
View Article and Find Full Text PDFJ Clin Oncol
February 2018
Devalkumar J. Rajyaguru, Reggie M. Thomes, and Patrick D. Conway, Gundersen Health System; Andrew J. Borgert and Angela L. Smith, Gundersen Lutheran Medical Foundation, La Crosse, WI; and Thorvardur R. Halfdanarson, Mark J. Truty, A. Nicholas Kurup, and Ronald S. Go, Mayo Clinic, Rochester, MN.
Purpose Data that guide selection of optimal local ablative therapy for the management localized hepatocellular carcinoma (HCC) are lacking. Because there are limited prospective comparative data for these treatment modalities, we aimed to compare the effectiveness of radiofrequency ablation (RFA) versus stereotactic body radiotherapy (SBRT) by using the National Cancer Database. Methods We conducted an observational study to compare the effectiveness of RFA versus SBRT in nonsurgically managed patients with stage I or II HCC.
View Article and Find Full Text PDFNeurosci Lett
January 2014
Department of Neurology, Huashan Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, No.12 Mid Wulumuqi Road, Shanghai 200040, PR China. Electronic address:
Curcumin is well known as an antioxidant and anti-inflammatory agent. In this study, we provided convincing evidence for the function of curcumin in neurite outgrowth of cortical neurons. We discovered that curcumin treatment could promote the number of processes, mean process length, and maximum process length of primary neurons, which were inhibited by reggie-1 siRNAs or extracellular signal-regulated kinase (ERK) 1/2 antagonist.
View Article and Find Full Text PDFAnn Med
June 2013
Department of Neurophysiology and Neuropharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Austria.
Introduction: Studies of synaptic plasticity using the marine mollusk Aplysia californica as model system have been successfully used to identify proteins involved in learning and memory. The importance of molecular elements regulated by the learning- related neurotransmitter serotonin in Aplysia can then be explored in rodent models and finally tested for their relevance for human physiology and pathology.
Materials And Methods: Herein, 2-DE gel-based electrophoresis has been used to investigate protein level changes after treatment with serotonin in Aplysia abdominal ganglia.
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