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Oxidative stress reactions in rats with pulmonary injuries induced by sulfur mustard (1 LD).
Hum Exp Toxicol
December 2024
Department of Respiration, The 80th Group Army Hospital of People's Liberation Army, Weifang, China.
Objective: Sulfur mustard (SM) is an important chemical warfare agent. The mechanisms underlying SM toxicity have not been completely elucidated. However, oxidative stress and the subsequent damage to macromolecules have been considered ascrucial steps in SM toxicity.
View Article and Find Full Text PDFExogenous salicylic acid reduces cadmium content in spinach (Spinacia oleracea L.) shoots under cadmium stress.
BMC Plant Biol
December 2024
College of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Background: Consumption of leafy vegetables is a primary route of cadmium (Cd) exposure in the human body. Salicylic acid (SA) is a major stress signaling molecule that alleviates Cd toxicity in various plants. Our study aimed to investigate the effects of different SA concentrations on spinach growth, cadmium accumulation, and stress resistance physiology under cadmium stress (50 µmol/L).
View Article and Find Full Text PDFEGCG inhibits the oxidative damage induced by TiO2-NPs in human colon cell lines.
Cell Mol Biol (Noisy-le-grand)
November 2024
School of Life Sciences, The Engineering Research Center of Sustainable Development and Utilization of Biomass Energy, Yunnan Normal University, Kunming 650500, China.
To assess the protective effects of (-)-Epigallocatechin-3-gallate (EGCG), a natural antioxidant, against cellular oxidative damage induced by titanium dioxide nanoparticles (TiO2-NPs), Human Colon cells NCM460 and Colon Cancer cells SW620 were selected for this study. The cells were divided into three groups: control group, TiO2-NPs (80 μg/mL) exposure group, and EGCG (20 μmol/L)+TiO2-NPs (80 μg/mL) co-exposure group. The study evaluated the precipitation rate of TiO2-NPs influenced by EGCG in a cell-free system.
View Article and Find Full Text PDFCyclosporine A causes gingival overgrowth via reduced G1 cell cycle arrest in gingival fibroblasts.
PLoS One
December 2024
Department of Biochemistry and Molecular Biology, Nihon University School of Dentistry at Matsudo, Matsudo, Chiba, Japan.
Gingival overgrowth caused by cyclosporine A is due to increased fibroblast proliferation in gingival tissues. Cell cycle system balances proliferation and anti-proliferation of gingival fibroblasts and plays a role in the maintenance of its population in gingival tissues. When cells detect and respond to abnormalities (e.
View Article and Find Full Text PDFTetramethyl Cucurbit[6]uril-Porphyrin Supramolecular Polymer Enhances Photosensitization.
Int J Mol Sci
December 2024
School of Basic Medical Sciences/School of Medical Humanities, Guizhou Medical University, Guiyang 550025, China.
Porphyrins serve as photosensitizers (PS) in the realm of cancer photodynamic therapy (PDT). Upon excitation by laser light, porphyrins are capable of converting molecular oxygen into highly cytotoxic singlet oxygen (O). However, the rigid π-conjugated structure of porphyrins frequently results in the formation of aggregates in aqueous solutions, which leads to the self-quenching of the excited state.
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