Aim Of The Study: To establish the prevalence of vertebral fractures according to age groups, sex and vertebral level in a sample of a Croatian urban population aged > or =50. We also tried to establish how many people had been diagnosed with osteoporosis by their family physician.
Participants And Methods: Lateral thoracic and lumbar spinal radiographs were obtained in 425 ambulatory people (156 men and 269 women) aged > or =50 and living in the community as a random sample of the City of Zagreb (Croatia) population. An interviewer-administered questionnaire was used to obtain information on prior traumatic vertebral fractures and whether the person had been diagnosed with osteoporosis. Vertebral fractures in the population sample were defined using the morphometric method proposed by McCloskey et al., and normal values of the ratios of dimensions in nonfractured vertebrae with the iterative algorithm described by Melton et al.
Results: The prevalence of individuals with vertebral fractures was 11.8% (15.8% of men and 9.7% of women), ranking Zagreb mid-scale among other European cities. The prevalence of individuals with vertebral fractures rose with age. Sixty-nine (1.24%) of 5525 analysed vertebrae had been fractured. The most common fractures were those of lower thoracic and upper lumbar vertebrae. The elderly tend to sustain multiple fractures. Forty-one (9.6%) people had been previously diagnosed as having osteoporosis. Extrapolation to the Croatian population implies that approximately 90,000 men and 77,000 women aged > or =50 have vertebral fractures.
Conclusion: Vertebral osteoporotic fractures are common in the Croatian population aged > or =50; however, awareness of osteoporosis appears to be low.
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http://dx.doi.org/10.1007/s00508-004-0292-9 | DOI Listing |
Adv Exp Med Biol
January 2025
Department of Stem Cells & Regenerative Medicine, Centre for Interdisciplinary Research, D Y Patil Education Society (Deemed to be University), Kolhapur, India.
Bone tissue engineering is a promising field that aims to rebuild the bone tissue using biomaterials, cells, and signaling molecules. Materials like natural and synthetic polymers, inorganic materials, and composite materials are used to create scaffolds that mimic the hierarchical microstructure of bone. Stem cells, particularly mesenchymal stem cells (MSCs), play a crucial role in bone tissue engineering by promoting tissue regeneration and modulating the immune response.
View Article and Find Full Text PDFInjury
January 2025
Department of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany; Department of Trauma, Hand- and Reconstructive Surgery, University Hospital Giessen, Giessen, Germany. Electronic address:
Purpose: Standard operating procedures aim to achieve a standardized and assumedly high-quality therapy. However, in orthopaedic surgery, the aspect of temporal urgency is often based on surgical tradition and experience. At a time of evidence-based medicine, it is necessary to question these temporal guidelines.
View Article and Find Full Text PDFJ Comput Assist Tomogr
January 2025
Department of Radiological Sciences.
Objective: This study evaluated the performance of a deep learning-based vertebral compression fracture (VCF) detection tool in patients with incidental VCF. The purpose of this study was to validate this tool across multiple sites and multiple vendors.
Methods: This was a retrospective, multicenter, multinational blinded study using anonymized chest and abdominal CT scans performed for indications other than VCF in patients ≥50 years old.
Sci Rep
January 2025
Department of Orthopaedics, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical University, #199 Jiefang South Road, Xuzhou, 221009, JiangSu Province, China.
Subsequent vertebral fracture (SVF) is a common and refractory complication after percutaneous vertebral augmentation (PVA) for osteoporotic vertebral compression fracture (OVCF). Computed tomography (CT)-based Hounsfeld units (HU) and magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score can evaluate osteoporosis quantitatively, hyperlipidemia(HLP) might affect measurement result of VBQ score. The primary objective of this study is to compare the predictive capabilities of HU and VBQ for SVF, and to clarify the impact of hyperlipidemia on the predictive abilities.
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