Coding information is the main source of heterogeneity (non-randomness) in the sequences of microbial genomes. The heterogeneity corresponds to a cluster structure in triplet distributions of relatively short genomic fragments (200-400 bp). We found a universal 7-cluster structure in microbial genomic sequences and explained its properties. We show that codon usage of bacterial genomes is a multi-linear function of their genomic G+C-content with high accuracy. Based on the analysis of 143 completely sequenced bacterial genomes available in Genbank in August 2004, we show that there are four "pure" types of the 7-cluster structure observed. All 143 cluster animated 3D-scatters are collected in a database which is made available on our web-site (http://www.ihes.fr/~zinovyev/7clusters). The findings can be readily introduced into software for gene prediction, sequence alignment or microbial genomes classification.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
First-Principles Study of Titanium-Doped B Cluster for High Capacity Hydrogen Storage.
Molecules
December 2024
School of Physics and Electronic Science, Zunyi Normal University, Zunyi 563006, China.
The geometrical structure, stability, electronic properties, and hydrogen storage capabilities of a titanium-doped B cluster was calculated using density functional theory computations. The results show that the TiB cluster is predicted to be stable under near-ambient conditions based on an ab initio molecular dynamic simulation. The transition state analysis found that the H molecule can dissociate on the TIB cluster surface to form a hydride cluster.
View Article and Find Full Text PDFDoping Copper(I) in Ag Cluster for Circularly Polarized OLEDs with External Quantum Efficiency of 26.7 .
Angew Chem Int Ed Engl
December 2024
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian, 350002, China.
Hetero-metal doping or substitution to create alloy clusters is a highly appealing strategy for improving physicochemical characteristics as well as tailoring optical and electronic properties, although high-yield synthesis of alloy clusters with precise positioning of doped metals is a daunting challenge. Herein, we manifest rational synthesis of chiral alloy cluster enantiomers R/S-AgCu in 85 %-87 % yield by replacing one Ag(I) atom with Cu(I) in homometallic clusters R/S-Ag, achieving circularly polarized luminescence (CPL) with a quantum yield beyond 90 %. As a small energy gap (ca.
View Article and Find Full Text PDFDensity functional theory-based study on the structural, electronic and spectral properties of gas-phase PbMg ( = 2-12) clusters.
R Soc Open Sci
September 2024
School of Public Health, Hubei University of Medicine, Shiyan 442000, People's Republic of China.
Article Synopsis
- The study utilized CALYPSO software to discover and analyze the gas-phase structures of PbMg clusters, focusing on sizes ranging from 2 to 12 atoms.
- Density functional theory was employed for structural optimization and to assess various properties, including stability, charge distribution, and spectroscopic characteristics of low-energy isomers.
- The findings indicated that the most stable isomer serves as the cluster ground state, contributing valuable insights for future experimental work on magnesium-based clusters.
Probing the Structures and Lanthanum-Lanthanum Bonding in LaB ( = 4-6) Clusters.
Inorg Chem
September 2024
Department of Chemistry, Brown University, Providence, Rhode Island 02912, United States.
We report an investigation on the structures and chemical bonding in a series of di-lanthanum boron clusters, LaB ( = 4-6), using photoelectron spectroscopy and theoretical calculations. Well-resolved photoelectron spectra are obtained and used to verify the global minima of the lanthanide boron clusters. The structures of LaB and LaB are found to consist of open B and B rings, respectively, around the La dimer equatorially.
View Article and Find Full Text PDFImpact of COVID-19 Pandemic on Routine Immunization Among Tribal Children in Odisha: A Rapid Epidemiological Survey.
Indian Pediatr
July 2024
Department of Community Medicine and Family Medicine, AIIMS Bhubaneswar, Odisha, India.
Objective: To assess the impact of COVID-19 on immunization coverage and delayed vaccination among tribal children in the Khordha district of Odisha state.
Methods: A cross-sectional rapid epidemiological survey was conducted using a standard WHO (30 × 7) cluster survey with 30 tribal villages under the Community Health Centre (CHC), Mendhasala, Odisha, as clusters and seven children from each cluster. A total of 14 children from each cluster; seven each born in 2019 (2019 cohort) and 2020 (2020 cohort), amounting to 420 children were included.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!